AChE/BChE/MAO-B-IN-1

Modify Date: 2024-01-12 19:03:49

AChE/BChE/MAO-B-IN-1 structure	Common Name	AChE/BChE/MAO-B-IN-1
	CAS Number	2416910-82-0	Molecular Weight	324.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₄N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AChE/BChE/MAO-B-IN-1

AChE/BChE/MAO-B-IN-1 (Compound 10) is a reversible and non-time-dependent AChE, BChE and MAO-B inhibitor with IC50 values of 7.31, 0.56 and 26.1 μM for hAChE, hBChE and hMAO-B, respectively. AChE/BChE/MAO-B-IN-1 can cross the BBB and shows neuroprotective effects without cytotoxicity[1].

Name	AChE/BChE/MAO-B-IN-1

Description	AChE/BChE/MAO-B-IN-1 (Compound 10) is a reversible and non-time-dependent AChE, BChE and MAO-B inhibitor with IC50 values of 7.31, 0.56 and 26.1 μM for hAChE, hBChE and hMAO-B, respectively. AChE/BChE/MAO-B-IN-1 can cross the BBB and shows neuroprotective effects without cytotoxicity[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	MAO-B:26.1 μM (IC50) hAChE:7.31 μM (IC50) hBChE:0.56 μM (IC50)
In Vitro	AChE/BChE/MAO-B-IN-1 (Compound 10) prevents amyloid β1-42 (Aβ1-42)-induced neuronal cell death[1].
References	[1]. Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282.

Molecular Formula	C₂₀H₂₄N₂O₂
Molecular Weight	324.42

AChE/BChE/MAO-B-IN-1

Use of AChE/BChE/MAO-B-IN-1

Names

AChE/BChE/MAO-B-IN-1 Biological Activity

Chemical & Physical Properties