GDC-6036
Modify Date: 2024-01-04 13:10:19
GDC-6036 structure
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Common Name | GDC-6036 | ||
|---|---|---|---|---|
| CAS Number | 2417987-45-0 | Molecular Weight | 622.06 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H32ClF4N7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GDC-6036GDC-6036 (compound 17a) is a potent K-Ras G12C inhibitor with an IC50 of <0.01 μM. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylation HCC1171 cells[1]. |
| Name | GDC-6036 |
|---|
| Description | GDC-6036 (compound 17a) is a potent K-Ras G12C inhibitor with an IC50 of <0.01 μM. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylation HCC1171 cells[1]. |
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| Related Catalog | |
| Target |
K-Ras(G12C):<0.01 μM (IC50) |
| References |
[1]. Sushant Malhotra, et al. Fused ring compounds. WO2020097537A2. |
| Molecular Formula | C29H32ClF4N7O2 |
|---|---|
| Molecular Weight | 622.06 |