4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline
![4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline Structure](https://image.chemsrc.com/caspic/483/2425-95-8.png)
4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline structure
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Common Name | 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline | ||
|---|---|---|---|---|
| CAS Number | 2425-95-8 | Molecular Weight | 252.27100 | |
| Density | 1.301g/cm3 | Boiling Point | 508.1ºC at 760mmHg | |
| Molecular Formula | C14H12N4O | Melting Point | 250-254 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 261.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.301g/cm3 |
|---|---|
| Boiling Point | 508.1ºC at 760mmHg |
| Melting Point | 250-254 °C(lit.) |
| Molecular Formula | C14H12N4O |
| Molecular Weight | 252.27100 |
| Flash Point | 261.1ºC |
| Exact Mass | 252.10100 |
| PSA | 90.96000 |
| LogP | 3.73040 |
| Vapour Pressure | 1.91E-10mmHg at 25°C |
| Index of Refraction | 1.669 |
| InChIKey | MJZXFMSIHMJQBW-UHFFFAOYSA-N |
| SMILES | Nc1ccc(-c2nnc(-c3ccc(N)cc3)o2)cc1 |
| Storage condition | −20°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2934999090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
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| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Sensitization of group III and IV muscle afferents in the mouse after ischemia and reperfusion injury.
J. Pain 15(12) , 1257-70, (2015) Ischemic myalgia is a unique type of muscle pain in the patient population. The role that discrete muscle afferent subpopulations play in the generation of pain during ischemic events, however, has ye... |
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Sensitive and Selective Determination of Orotic Acid in Biological Specimens Using a Novel Fluorogenic Reaction.
J. Fluoresc. 25 , 1005-11, (2015) Orotic acid is an intermediate in the synthesis pathway of uridine-5'-monophosphate, and increases in body fluids of patients suffering from hereditary disorders such as orotic aciduria and hyperammon... |
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Cytofluorometric determination of nuclear DNA in living and preserved algae.
Stain Technol. 57(5) , 273-82, (1982) Three DNA-localizing fluorochromes used in conjunction with epi (incident) UV illumination were examined for sensitivity and selectivity for the cytofluorometric determination of nuclear DNA in ten sp... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-(n-aminophenyl)-5-(n-aminophenyl)-1,3,4-oxadiazole |
| 2,5-BIS(4-AMINOPHENYL)-1,3,4-OXADIAZOLE |
| 2,5-bis(4-aminophenylene)-1,3,4-oxadiazole |
| EINECS 219-373-8 |
| 2,5-bis(p-aminophenyl)-1,3,4-oxadiazole |
| 4,4'-(1,3,4-Oxadiazole-2,5-diyl)dianiline |
| 2,5-Bis-(4-aminophenyl)-1,3,4-oxadiazole |
| 2,5-bis(4-aminobenzoyl)-1,3,4-oxadiazole |
| MFCD00042667 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the boiling point of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline? |
| A: Boiling point of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline is 508.1ºC at 760mmHg. |
| Q: What English synonyms does 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline have? |
| A: English synonyms of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline: 2-(n-aminophenyl)-5-(n-aminophenyl)-1,3,4-oxadiazole, 2,5-BIS(4-AMINOPHENYL)-1,3,4-OXADIAZOLE, 2,5-bis(4-aminophenylene)-1,3,4-oxadiazole, EINECS 219-373-8, 2,5-bis(p-aminophenyl)-1,3,4-oxadiazole, 4,4'-(1,3,4-Oxadiazole-2,5-diyl)dianiline, 2,5-Bis-(4-aminophenyl)-1,3,4-oxadiazole, 2,5-bis(4-aminobenzoyl)-1,3,4-oxadiazole, MFCD00042667. |
| Q: What is the CAS number of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline? |
| A: CAS number of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline is 2425-95-8. |
| Q: What are the upstream materials of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline? |
| A: Related upstream materials(CAS) of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline: 1044-49-1;16106-38-0;150-13-0;62-23-7;122-04-3;636-97-5;556-18-3;5351-17-7. |
| Q: What is the safety information for 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline? |
| A: Safety information for 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline: S26-S37/39. |
| Q: What is the InChIKey of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline? |
| A: InChIKey of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline is MJZXFMSIHMJQBW-UHFFFAOYSA-N. |
| Q: What is the polar surface area (PSA) of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline? |
| A: Polar surface area (PSA) of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline is 90.96000. |
| Q: What is the LogP of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline? |
| A: LogP of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline is 3.73040. |
| Q: What is the English name of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline? |
| A: The English name of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline is 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline. |
| Q: What is the SMILES notation of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline? |
| A: SMILES notation of 4-[5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl]aniline is Nc1ccc(-c2nnc(-c3ccc(N)cc3)o2)cc1. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |