ZMVR DZ

Modify Date: 2024-01-03 19:30:49

ZMVR DZ Structure
ZMVR DZ structure
Common Name ZMVR DZ
CAS Number 5351-17-7 Molecular Weight 151.17
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C7H9N3O Melting Point 225-227 °C(lit.)
MSDS Chinese USA Flash Point N/A

 Use of ZMVR DZ


4-Aminobenzohydrazide is an irreversible MPO myeloperoxidase inhibitor with an IC50 of 0.3 µM[1]. It is used for the research of subacute stroke[2].

 Names

Name 4-Aminobenzohydrazide
Synonym More Synonyms

 ZMVR DZ Biological Activity

Description 4-Aminobenzohydrazide is an irreversible MPO myeloperoxidase inhibitor with an IC50 of 0.3 µM[1]. It is used for the research of subacute stroke[2].
Related Catalog
References

[1]. Kettle AJ, et al. Inhibition of myeloperoxidase by benzoic acid hydrazides. Biochem J. 1995 Jun 1;308 ( Pt 2)(Pt 2):559-63.

[2]. Forghani R, et al. Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke. J Cereb Blood Flow Metab. 2015 Mar;35(3):485-93.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Melting Point 225-227 °C(lit.)
Molecular Formula C7H9N3O
Molecular Weight 151.17
Exact Mass 151.074554
PSA 81.14000
LogP -0.75
Index of Refraction 1.641

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG2580000
CHEMICAL NAME :
Benzoic acid, p-amino-, hydrazide
CAS REGISTRY NUMBER :
5351-17-7
BEILSTEIN REFERENCE NO. :
0639053
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H9-N3-O
MOLECULAR WEIGHT :
151.19
WISWESSER LINE NOTATION :
ZNUYQR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01358

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DG2580000
HS Code 2928000090

 Synthetic Route

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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 Synonyms

EINECS 226-324-4
p-Aminobenzoyl Hydrazide
4-aminobenzhydrazide
Aminostimil
(4-Aminobenzoyl)hydrazide
Amben hydrazide
p-Aminobenzhydrazide
4-Aminobenzoylhydrazide
4-aminobenzenecarbonylhydrazine
4-Aminobenzoic acid hydrazide
4-Aminobenzohydrazide
ZMVR DZ
Benzoic acid, 4-amino-, hydrazide
4-Aminobenzoylhydrazine
4-Aminobenzoic hydrazide
MFCD00007606
p-Aminobenzoic acid hydrazide
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