Vidarabine monohydrate

Modify Date: 2024-01-02 18:05:28

Vidarabine monohydrate Structure
Vidarabine monohydrate structure
Common Name Vidarabine monohydrate
CAS Number 24356-66-9 Molecular Weight 285.257
Density N/A Boiling Point N/A
Molecular Formula C10H15N5O5 Melting Point 257.0-257.5ºC (0.4 H2O)
MSDS N/A Flash Point N/A

 Use of Vidarabine monohydrate


Vidarabine monohydrate is an adenine arabinoside. Vidarabine monohydrate an antiviral drug which is active against herpes simplex viruses (HSV) and varicella zoster viruses[1].

 Names

Name 9-beta-D-arabinofuranosyl-9H-purine-6-amine monohydrate
Synonym More Synonyms

 Vidarabine monohydrate Biological Activity

Description Vidarabine monohydrate is an adenine arabinoside. Vidarabine monohydrate an antiviral drug which is active against herpes simplex viruses (HSV) and varicella zoster viruses[1].
Related Catalog
References

[1]. Whitley, R., et al., Vidarabine: a preliminary review of its pharmacological properties and therapeutic use. Drugs, 1980. 20(4): p. 267-82.

 Chemical & Physical Properties

Melting Point 257.0-257.5ºC (0.4 H2O)
Molecular Formula C10H15N5O5
Molecular Weight 285.257
Exact Mass 285.107330
PSA 148.77000

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU6210000
CHEMICAL NAME :
Adenine, 9-beta-D-arabinofuranosyl-, monohydrate
CAS REGISTRY NUMBER :
24356-66-9
LAST UPDATED :
199703
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H13-N5-O4.H2-O
MOLECULAR WEIGHT :
285.30
WISWESSER LINE NOTATION :
T56 BN DN FN HNJ IZ D- ET5OTJ B1Q CQ DQ &QH *D-ARABINO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>7950 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI) 1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year: -,180,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4677 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Gastrointestinal - peritonitis
REFERENCE :
AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI) 1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year: -,180,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2367 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 454 (estimated) No. of Female Employees: 230 (estimated)

 Safety Information

Hazard Codes Xi
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

adenine arabinoside
9H-purin-6-amine, 9-b-D-arabinofuranosyl-, hydrate (1:1)
9-(β-D-Arabinofuranosyl)adenine Monohydrate
Arasena-A
7H-Purine-7-carboxylic acid,6-amino-,phenylmethyl ester
9b-D-Arabinofuranosyladenine Monohydrate
9-(β-D-Arabinofuranosyl)-9H-purin-6-amine hydrate
(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydro-3,4-furandiol hydrate
9-(β-D-Arabinofuranosyl)-9H-purin-6-amine hydrate (1:1)
spongoadenosine
9-(b-D-arabinofuranosyl)-9H-purin-6-amine hydrate (1:1)
(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxyméthyl)tétrahydrofurane-3,4-diol hydrate
6-amino-purine-7-carboxylic acid benzyl ester
Vira ATM
Ara-A Monohydrate
(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrate
9-(β-D-Arabinofuranosyl)-9H-purin-6-aminhydrat
7-Carbobenzoxy-adenin
9-β-D-arabinofuranosyl-9H-purin-6-amine hydrate
Benzyl 6-aminopurin-7-carboxylat
Adenine 9-β-D-Arabinofuranoside Monohydrate
(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diolhydrat
9b-D-Arabinofuranosyl-9H-purine-6-amine Monohydrate
arabinosyladenine
b-D-Arabinofuranosyladenine Monohydrate
Adenin-7-carbonsaeurebenzylester
9H-Purin-6-amine, 9-β-D-arabinofuranosyl-, hydrate (1:1)
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.