5-Methoxyindole-3-acetonitrile

Modify Date: 2024-01-10 16:51:33

5-Methoxyindole-3-acetonitrile Structure
5-Methoxyindole-3-acetonitrile structure
Common Name 5-Methoxyindole-3-acetonitrile
CAS Number 2436-17-1 Molecular Weight 186.21000
Density 1.224g/cm3 Boiling Point 408.3ºC at 760mmHg
Molecular Formula C11H10N2O Melting Point 65-69 °C(lit.)
MSDS Chinese USA Flash Point 200.7ºC

 Names

Name 2-(5-Methoxy-1H-indol-3-yl)acetonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.224g/cm3
Boiling Point 408.3ºC at 760mmHg
Melting Point 65-69 °C(lit.)
Molecular Formula C11H10N2O
Molecular Weight 186.21000
Flash Point 200.7ºC
Exact Mass 186.07900
PSA 48.81000
LogP 2.24258
Vapour Pressure 7.09E-07mmHg at 25°C
Index of Refraction 1.638

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

~71%

5-Methoxyindole-3-acetonitrile Structure

5-Methoxyindole...

CAS#:2436-17-1

Literature: Wu, Jiang-Ping; Wang, Ji; Abeywardane, Asitha; Andersen, Denise; Emmanuel, Michel; Gautschi, Elda; Goldberg, Daniel R.; Kashem, Mohammed A.; Lukas, Susan; Mao, Wang; Martin, Leslie; Morwick, Tina; Moss, Neil; Pargellis, Christopher; Patel, Usha R.; Patnaude, Lori; Peet, Gregory W.; Skow, Donna; Snow, Roger J.; Ward, Yancey; Werneburg, Brian; White, Andre Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 16 p. 4664 - 4669

~%

5-Methoxyindole-3-acetonitrile Structure

5-Methoxyindole...

CAS#:2436-17-1

Literature: Justus Liebigs Annalen der Chemie, , vol. 513, p. 1,18

~%

5-Methoxyindole-3-acetonitrile Structure

5-Methoxyindole...

CAS#:2436-17-1

Literature: Tsotinis, Andrew; Vlachou, Margarita; Papahatjis, Demetris P.; Calogeropoulou, Theodora; Nikas, Spyros P.; Garratt, Peter J.; Piccio, Vincent; Vonhoff, Stefan; Davidson, Kathryn; Teh, Muy-Teck; Sugden, David Journal of Medicinal Chemistry, 2006 , vol. 49, # 12 p. 3509 - 3519

~88%

5-Methoxyindole-3-acetonitrile Structure

5-Methoxyindole...

CAS#:2436-17-1

Literature: Perez-Alvarez, Victor; Morales-Rios, Martha S.; Hong, Enrique; Joseph-Nathan, Pedro Journal of Pharmacy and Pharmacology, 1997 , vol. 49, # 3 p. 246 - 252

~%

5-Methoxyindole-3-acetonitrile Structure

5-Methoxyindole...

CAS#:2436-17-1

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 9 p. 2571 - 2574

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-(Cyanomethyl)-5-methoxyindole
2-(5-methoxy-1H-indol-3-yl)acetonitrile
MFCD02094163