DHODH-IN-7
Modify Date: 2024-01-10 12:38:32
DHODH-IN-7 structure
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Common Name | DHODH-IN-7 | ||
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| CAS Number | 2029049-77-0 | Molecular Weight | 390.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H21F3N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DHODH-IN-7DHODH-IN-7 is a human dihydroorotate dehydrogenase (DHODH) inhibitor, with an IC50 of 0.91 μM. DHODH-IN-7 induces differentiation in acute myeloid leukemia[1]. |
| Name | DHODH-IN-7 |
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| Description | DHODH-IN-7 is a human dihydroorotate dehydrogenase (DHODH) inhibitor, with an IC50 of 0.91 μM. DHODH-IN-7 induces differentiation in acute myeloid leukemia[1]. |
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| Related Catalog | |
| In Vitro | The lysozyme-GFPER-HoxA9 murine cell line (ER-HOX-GFP) and the THP1 and U937 human AML cell lines were cultured with compounds in a 4-day differentiation assay. DHODH-IN-7 shows EC50s of 3.6, 2.7, and 2.5 μM for ER-HOX-GFP, THP1 and U937 human AML cell lines, respectively[1]. |
| References |
| Molecular Formula | C21H21F3N2O2 |
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| Molecular Weight | 390.40 |
| Hazard Codes | Xi |
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