α-Amylase/α-Glucosidase-IN-2

Modify Date: 2024-01-13 23:08:32

α-Amylase/α-Glucosidase-IN-2 Structure
α-Amylase/α-Glucosidase-IN-2 structure
Common Name α-Amylase/α-Glucosidase-IN-2
CAS Number 2446063-14-3 Molecular Weight 385.85
Density N/A Boiling Point N/A
Molecular Formula C22H16ClN5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of α-Amylase/α-Glucosidase-IN-2


α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent α-amylase and α-glucosidase dual inhibitor with IC50 values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications[1].

 Names

Name α-Amylase/α-Glucosidase-IN-2

 α-Amylase/α-Glucosidase-IN-2 Biological Activity

Description α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent α-amylase and α-glucosidase dual inhibitor with IC50 values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications[1].
Related Catalog
Target

IC50: 13.02 µM (α-amylase); 13.09 µM (α-glucosidase)[1].

References

[1]. Shamim S, et al. Synthesis and screening of (E)-3-(2-benzylidenehydrazinyl)-5,6-diphenyl-1,2,4-triazine analogs as novel dual inhibitors of α-amylase and α-glucosidase. Bioorg Chem. 2020 Aug;101:103979.

 Chemical & Physical Properties

Molecular Formula C22H16ClN5
Molecular Weight 385.85
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