Aldose reductase-IN-4

Modify Date: 2025-08-26 16:36:08

Aldose reductase-IN-4 Structure
Aldose reductase-IN-4 structure
Common Name Aldose reductase-IN-4
CAS Number 2446136-17-8 Molecular Weight 291.30
Density N/A Boiling Point N/A
Molecular Formula C14H10FNO3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aldose reductase-IN-4


Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].

 Names

Name Aldose reductase-IN-4

 Aldose reductase-IN-4 Biological Activity

Description Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].
Related Catalog
Target

IC50: 11.70 μM (Aldehyde reductase 1) and 0.98 μM (Aldehyde reductase 2)[1]

References

[1]. Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28(15):115575.

 Chemical & Physical Properties

Molecular Formula C14H10FNO3S
Molecular Weight 291.30
InChIKey RNGRVWMFCJQROU-UHFFFAOYSA-N
SMILES O=S(=O)(c1ccc(O)c(F)c1)n1ccc2ccccc21
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