Taragarestrant meglumine

Modify Date: 2024-04-03 08:49:45

Taragarestrant meglumine Structure
Taragarestrant meglumine structure
 Common Name Taragarestrant meglumine
CAS Number 2446618-18-2 Molecular Weight 670.60
Density N/A Boiling Point N/A
Molecular Formula C32H42Cl2FN3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Taragarestrant meglumine


Taragarestrant (D-0502) meglumine is a potent, orally active and selective estrogen receptor degrader (SERD). Taragarestrant meglumine shows potent activity in various ER+ breast cancer cell lines and xenograft models[1][2].

 Names

Name Taragarestrant meglumine

 Taragarestrant meglumine Biological Activity

Description Taragarestrant (D-0502) meglumine is a potent, orally active and selective estrogen receptor degrader (SERD). Taragarestrant meglumine shows potent activity in various ER+ breast cancer cell lines and xenograft models[1][2].
Related Catalog
In Vivo Taragarestrant (D-0502) exhibits superior PK profiles suitable for clinical development[1].
References

[1]. Lin WY, et, al. Abstract 5776: Pharmacologic and PK/PD study of D-0502: An orally bioavailable SERD with potent antitumor activity in ER-positive breast cancer cell lines and xenograft models. 2018 Jul 1;78(13):5776.

[2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical.

 Chemical & Physical Properties

Molecular Formula C32H42Cl2FN3O7
Molecular Weight 670.60
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