Paclitaxel succinate NHS ester
Modify Date: 2024-01-13 15:41:10
Paclitaxel succinate NHS ester structure
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Common Name | Paclitaxel succinate NHS ester | ||
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| CAS Number | 245110-80-9 | Molecular Weight | 1051.051 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C55H58N2O19 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Paclitaxel succinate NHS esterDCN10809, also known as Paclitaxel succinate NHS ester, is a paclitaxel derivative with a succinic acid linker, in which the carboxy group is activated with an NHS ester. The NHS ester group is highly reactive to amino group or hydroxy group, and can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-Succinic acid is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research. |
| Name | (2α,5β,7β,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-({4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutanoyl}oxy)-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate |
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| Synonym | More Synonyms |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C55H58N2O19 |
| Molecular Weight | 1051.051 |
| Exact Mass | 1050.363403 |
| LogP | 6.91 |
| Index of Refraction | 1.636 |
| (2α,5β,7β,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-({4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutanoyl}oxy)-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en 
-2-yl benzoate |
| Benzenepropanoic acid, β-(benzoylamino)-α-[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,4-dioxobutoxy]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,1 2,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)- |