DBCO-PEG2-NHS ester

Modify Date: 2024-04-08 11:50:13

DBCO-PEG2-NHS ester Structure
DBCO-PEG2-NHS ester structure
Common Name DBCO-PEG2-NHS ester
CAS Number 2585653-12-7 Molecular Weight 561.58
Density N/A Boiling Point N/A
Molecular Formula C30H31N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG2-NHS ester


DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only[1].

 Names

Name DBCO-PEG2-NHS ester

 DBCO-PEG2-NHS ester Biological Activity

Description DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only[1].
Related Catalog
References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

 Chemical & Physical Properties

Molecular Formula C30H31N3O8
Molecular Weight 561.58