Iodoacetyl-PEG4-NHS ester

Modify Date: 2025-08-27 10:45:35

Iodoacetyl-PEG4-NHS ester Structure
Iodoacetyl-PEG4-NHS ester structure
Common Name Iodoacetyl-PEG4-NHS ester
CAS Number 2517899-65-7 Molecular Weight 530.31
Density N/A Boiling Point N/A
Molecular Formula C17H27IN2O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Iodoacetyl-PEG4-NHS ester


Iodoacetyl-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Iodoacetyl-PEG4-NHS ester

 Iodoacetyl-PEG4-NHS ester Biological Activity

Description Iodoacetyl-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H27IN2O9
Molecular Weight 530.31
InChIKey ZWXHWNWXEXCATP-UHFFFAOYSA-N
SMILES O=C(CI)NCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
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