Sphingosine (d14:1)

Modify Date: 2024-01-10 17:52:13

Sphingosine (d14:1) Structure
Sphingosine (d14:1) structure
Common Name Sphingosine (d14:1)
CAS Number 24558-60-9 Molecular Weight 243.38600
Density 0.963 g/cm3 Boiling Point 392.552ºC at 760 mmHg
Molecular Formula C14H29NO2 Melting Point N/A
MSDS N/A Flash Point 191.209ºC

 Use of Sphingosine (d14:1)


Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters[1].

 Names

Name (2S,3R,4E)-2-Amino-4-tetradecene-1,3-diol
Synonym More Synonyms

 Sphingosine (d14:1) Biological Activity

Description Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters[1].
Related Catalog
Target

PKC

References

[1]. Y A Hannun, et al. Regulation of protein kinase C by sphingosine and lysosphingolipids. Clin Chim Acta. 1989 Dec 15;185(3):333-45.

 Chemical & Physical Properties

Density 0.963 g/cm3
Boiling Point 392.552ºC at 760 mmHg
Molecular Formula C14H29NO2
Molecular Weight 243.38600
Flash Point 191.209ºC
Exact Mass 243.22000
PSA 66.48000
LogP 3.06410

 Synonyms

Tetradephing-4-enine
D-erythro-C14-sphingosine
(E)-D-erythro-2-AMino-4-tetradecene-1,3-diol
C14-Sphingosine
(2S,3R,E)-2-Amino-4-tetradecene-1,3-diol
(2S,3R)-amino-tetradeca-4-ene-1,3-diol