FNC-TP

Modify Date: 2024-01-09 20:19:25

FNC-TP structure	Common Name	FNC-TP
	CAS Number	2457357-99-0	Molecular Weight	526.16
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₄FN₆O₁₃P₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FNC-TP

FNC-TP is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV[1].

Name	FNC-TP

Description	FNC-TP is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Signaling Pathways >> Anti-infection >> HCV Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Signaling Pathways >> Anti-infection >> Reverse Transcriptase
Target	reverse transcriptase[1] HIV[1] HBV[1] HCV[1]
In Vitro	FNC (0.1-10 nM; 24-240 h) is found mainly to accumulate in these HIV-1 target cells, and the retention of FNC-TP is 2-4 times higher than in other types of cells[1].
In Vivo	FNC (1-6 mg/kg; a single p.o.) could enter rhesus macaque PBMCs and form the active nucleoside triphosphate FNC-TP[1].
References	[1]. Sun L, et, al. Mechanistic Insight into Antiretroviral Potency of 2'-Deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a Long-Lasting Effect on HIV-1 Prevention. J Med Chem. 2020 Aug 13;63(15):8554-8566.

Molecular Formula	C₉H₁₄FN₆O₁₃P₃
Molecular Weight	526.16

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: FNC-TP
Price: Click To Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: FNC-TP
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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