Influenza A virus-IN-6

Modify Date: 2024-01-29 23:36:10

Influenza A virus-IN-6 structure	Common Name	Influenza A virus-IN-6
	CAS Number	2464415-31-2	Molecular Weight	409.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₃N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Influenza A virus-IN-6

Influenza A virus-IN-6 (compound 16j) is a potent and selective influenza A virus inhibitor with an IC50 of 3.88 µM and CC50 of 36.64 µM. Influenza A virus-IN-6 shows anti-IAV activity with low cytotoxicity[1].

Name	Influenza A virus-IN-6

Description	Influenza A virus-IN-6 (compound 16j) is a potent and selective influenza A virus inhibitor with an IC50 of 3.88 µM and CC50 of 36.64 µM. Influenza A virus-IN-6 shows anti-IAV activity with low cytotoxicity[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Inflammation/Immunology
Target	IC50: 3.88 µM (influenza virus); CC50: 36.64 µM (influenza virus)[1]
In Vitro	Influenza A virus-IN-6 (compound 16j) shows anti-influenza virus activity with an IC50 of 0.41 µM in 293T-GLUC cells.
References	[1]. Zhang G, et al. Design, synthesis and in vitro anti-influenza A virus evaluation of novel quinazoline derivatives containing S-acetamide and NH-acetamide moieties at C-4. Eur J Med Chem. 2020 Nov 15;206:112706.

Molecular Formula	C₂₅H₂₃N₅O
Molecular Weight	409.48