3',5'-Dimethoxy-4'-hydroxyacetophenone

Modify Date: 2025-08-21 21:00:49

3',5'-Dimethoxy-4'-hydroxyacetophenone structure	Common Name	3',5'-Dimethoxy-4'-hydroxyacetophenone
	CAS Number	2478-38-8	Molecular Weight	196.200
	Density	1.2±0.1 g/cm3	Boiling Point	334.7±37.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₂O₄	Melting Point	124-127 °C(lit.)
	MSDS	Chinese USA	Flash Point	131.7±20.0 °C
	Symbol	GHS07	Signal Word	Warning

Use of 3',5'-Dimethoxy-4'-hydroxyacetophenone

Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself[1]. Acetosyringone enhances efficient Dunaliella transformation of Agrobacterium strains[2].

Name	acetosyringone
Synonym	More Synonyms

Description	Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself[1]. Acetosyringone enhances efficient Dunaliella transformation of Agrobacterium strains[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others Natural Products >> Phenols
In Vitro	Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself[1]. Acetosyringone enhances efficient Dunaliella transformation of Agrobacterium strains[2].
References	[1]. Xi J, et al. Acetosyringone treatment duration affects large T-DNA molecule transfer to rice callus. BMC Biotechnol. 2018 Aug 9;18(1):48. [2]. Srinivasan R, et al. Synergistic Action of D-Glucose and Acetosyringone on Agrobacterium Strains for Efficient Dunaliella Transformation. PLoS One. 2016 Jun 28;11(6):e0158322.

Density	1.2±0.1 g/cm3
Boiling Point	334.7±37.0 °C at 760 mmHg
Melting Point	124-127 °C(lit.)
Molecular Formula	C₁₀H₁₂O₄
Molecular Weight	196.200
Flash Point	131.7±20.0 °C
Exact Mass	196.073563
PSA	55.76000
LogP	1.23
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.528
Water Solubility	soluble

3',5'-Dimethoxy-4'-hydroxyacetophenone MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM8440000

CHEMICAL NAME :: Acetophenone, 3,5-dimethoxy-4-hydroxy-

CAS REGISTRY NUMBER :: 2478-38-8

BEILSTEIN REFERENCE NO. :: 1966119

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H12-O4

MOLECULAR WEIGHT :: 196.22

WISWESSER LINE NOTATION :: 1VR DQ CO1 EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCTKAG Bromatologia i Chemia Toksykologiczna. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.4- 1971- Volume(issue)/page/year: 14,301,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 650 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex)

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 7,178,1964

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	AM8440000
HS Code	2914509090

Precursor 8
CAS#:1136-86-3 3',4',5'-Trimet... CAS#:33900-62-8 3,5-DIMETHOXY-4... CAS#:944-99-0 Phenol, 2,6-dim... CAS#:871798-98-0 3,3'-dimethoxy-...
CAS#:14059-92-8 2,6-Dimethoxy-4... CAS#:39151-19-4 3′,5′-Dimethoxy... CAS#:51149-28-1 2-bromo-1-(4-hy... CAS#:91-10-1 Syringol
DownStream 9
CAS#:14059-92-8 2,6-Dimethoxy-4... CAS#:2151-18-0 1,2,3-Benzenetr... CAS#:28294-47-5 4'-ACETOXY-3',5... CAS#:7404-35-5 a-D-Glucopyrano...
CAS#:141243-24-5 3,5-Dimethoxy-4... CAS#:83-87-4 beta-d-glucose ... CAS#:86402-42-8 3,5-dimethoxy-4... CAS#:25878-60-8 1,2,3,4,6-penta...
CAS#:77439-76-0 3-Chloro-4-(dic...

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

The RING E3 Ligase KEEP ON GOING Modulates JASMONATE ZIM-DOMAIN12 Stability.

Plant Physiol. 169 , 1405-17, (2015)

Jasmonate (JA) signaling in plants is mediated by the JASMONATE ZIM-DOMAIN (JAZ) proteins that repress the activity of several transcription factors regulating JA-inducible gene expression. The hormon...

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...

Identification of rice cornichon as a possible cargo receptor for the Golgi-localized sodium transporter OsHKT1;3.

J. Exp. Bot. 66 , 2733-48, (2015)

Membrane proteins are synthesized and folded in the endoplasmic reticulum (ER), and continue their path to their site of residence along the secretory pathway. The COPII system has been identified as ...

Ethanone,1-(4-hydroxy-3,5-dimethoxyphenyl)

3',5'-Dimethoxy-4'-Hydroxyacetophenone

1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanone

Ethanone, 1-(4-hydroxy-3,5-dimethoxyphenyl)-

Acetosyringenin

3,5-Dimethoxy-4-hydroxyacetophenone

1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

3‘,5‘-Dimethoxy-4‘-hydroxyacetophenone

Syringylethanone

MFCD00008748

4'-Hydroxy-3',5'-dimethoxyacetophenone

EINECS 219-610-5

Acetosyringone

Acetophenone,4'-hydroxy-3',5'-dimethoxy

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Price: ￥550/10 mM * 1 mL in DMSO

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3',5'-Dimethoxy-4'-hydroxyacetophenone

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