BACE1-IN-12
Modify Date: 2024-01-10 15:27:13
BACE1-IN-12 structure
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Common Name | BACE1-IN-12 | ||
|---|---|---|---|---|
| CAS Number | 2479315-19-8 | Molecular Weight | 547.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H28Cl2N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BACE1-IN-12BACE1-IN-12 (compound 7g) is a potent and BBB-penetrated BACE1 inhibitor, with an IC50 of 8.9 µM. BACE1-IN-12 shows selective BuChE (butyrylcholinesterase) inhibitory activity with an IC50 of 3.2 µM. BACE1-IN-12 shows effective antioxidant effect with an IC50 of 10.2 μM (DPPH). BACE1-IN-12 might be served as a potential anti-Alzheimer agent[1]. |
| Name | BACE1-IN-12 |
|---|
| Description | BACE1-IN-12 (compound 7g) is a potent and BBB-penetrated BACE1 inhibitor, with an IC50 of 8.9 µM. BACE1-IN-12 shows selective BuChE (butyrylcholinesterase) inhibitory activity with an IC50 of 3.2 µM. BACE1-IN-12 shows effective antioxidant effect with an IC50 of 10.2 μM (DPPH). BACE1-IN-12 might be served as a potential anti-Alzheimer agent[1]. |
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| Related Catalog | |
| Target |
IC50: 8.9 ± 0.20 µM (BACE1), 3.2 ± 0.2 µM (BuChE)[1] |
| References |
| Molecular Formula | C29H28Cl2N6O |
|---|---|
| Molecular Weight | 547.48 |