Thiamine pyrophosphate-d3

Modify Date: 2024-01-03 20:25:00

Thiamine pyrophosphate-d3 Structure
Thiamine pyrophosphate-d3 structure
 Common Name Thiamine pyrophosphate-d3
CAS Number 2483831-79-2 Molecular Weight 463.79
Density N/A Boiling Point N/A
Molecular Formula C12H16D3ClN4O7P2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thiamine pyrophosphate-d3


Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.

 Names

Name Thiamine pyrophosphate-d3

 Thiamine pyrophosphate-d3 Biological Activity

Description Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula C12H16D3ClN4O7P2S
Molecular Weight 463.79
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