Cocarboxylase
Modify Date: 2024-01-02 19:04:10
Cocarboxylase structure
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Common Name | Cocarboxylase | ||
|---|---|---|---|---|
| CAS Number | 154-87-0 | Molecular Weight | 460.767 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H19ClN4O7P2S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of CocarboxylaseThiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. |
| Name | thiamine(1+) diphosphate |
|---|---|
| Synonym | More Synonyms |
| Description | Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| Molecular Formula | C12H19ClN4O7P2S |
|---|---|
| Molecular Weight | 460.767 |
| Exact Mass | 460.013824 |
| PSA | 216.83000 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Risk Phrases | R22 |
| Safety Phrases | S22-S24/25 |
| RIDADR | 1759 |
| WGK Germany | 3 |
| RTECS | XI7552000 |
| Packaging Group | III |
| Hazard Class | 8 |
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Cocarboxylase CAS#:154-87-0 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 618, p. 210,215, 219 Yakugaku Zasshi, , vol. 76, p. 1314,1317 Chem.Abstr., , p. 3607 Helvetica Chimica Acta, , vol. 32, p. 1478,1483 Journal of Vitaminology, , vol. 5, p. 44,49 |
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Cocarboxylase CAS#:154-87-0 |
| Literature: Chemische Berichte, , vol. 95, p. 767 - 772 |
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Cocarboxylase CAS#:154-87-0 |
| Literature: Chemische Berichte, , vol. 95, p. 767 - 772 |
![3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]thiazolium structure](https://image.chemsrc.com/caspic/330/10023-48-0.png)
CAS#:532-40-1|
Regulation at multiple levels control the expression of folate transporters in liver cells in conditions of ethanol exposure and folate deficiency.
Biofactors 41 , 232-41, (2015) Complex regulatory mechanisms control the expression of folate transporters within cells. Liver is the primary reserve of the folate stores within the body. As excessive alcohol consumption or ineffic... |
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The Janus kinase 2 inhibitor fedratinib inhibits thiamine uptake: a putative mechanism for the onset of Wernicke's encephalopathy.
Drug Metab. Dispos. 42(10) , 1656-62, (2014) The clinical development of fedratinib, a Janus kinase (JAK2) inhibitor, was terminated after reports of Wernicke's encephalopathy in myelofibrosis patients. Since Wernicke's encephalopathy is induced... |
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Gene Transfer Efficiency in Gonococcal Biofilms: Role of Biofilm Age, Architecture, and Pilin Antigenic Variation.
J. Bacteriol. 197 , 2422-31, (2015) Extracellular DNA is an important structural component of many bacterial biofilms. It is unknown, however, to which extent external DNA is used to transfer genes by means of transformation. Here, we q... |
| 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium chloride |
| TDP |
| Vitamin B1 Pyrophosphoric Acid Ester Chloride |
| 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-[2-[[hydroxy(phosphonooxy)phosphinyl]oxy]ethyl]-4-methylthiazolium Chloride |
| 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-{[hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium chloride |
| Cocarboxylase |
| MFCD00038740 |
| 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-3,5-dioxa-4,6-diphosphahex-1-yl)thiazolium Chloride P,P'-Dioxide |
| cocarboxylasum [INN_la] |
| Vitamin B1 Pyrophosphate Chloride |
| Thiamine pyrophosphate |
| Aneurinepyrophosphoric acid Cocarboxylase Thiamine pyrophosphate chloride |
| 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)thiazolium Chloride |
| Co-B1 |
| tpp |
| EINECS 205-230-7 |
| Bioxilasi |
| thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-[2-[[hydroxy(phosphonooxy)phosphinyl]oxy]ethyl]-4-methyl-, chloride (1:1) |
| TPP (VAN) |
| Thiamine Pyrophosphoric Acid Ester Chloride |
| Thiamine Pyrophosphate Chloride |
| thiamine(1+) diphosphate chloride |
| Thiamine Diphosphate Ester Chloride |
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