4-Amino-3-chlorobenzoic acid
4-Amino-3-chlorobenzoic acid structure
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Common Name | 4-Amino-3-chlorobenzoic acid | ||
|---|---|---|---|---|
| CAS Number | 2486-71-7 | Molecular Weight | 171.581 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 341.2±27.0 °C at 760 mmHg | |
| Molecular Formula | C7H6ClNO2 | Melting Point | 228 °C | |
| MSDS | Chinese USA | Flash Point | 160.2±23.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | 4-Amino-3-chlorobenzoic acid |
|---|---|
| Synonym | More Synonyms |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 341.2±27.0 °C at 760 mmHg |
| Melting Point | 228 °C |
| Molecular Formula | C7H6ClNO2 |
| Molecular Weight | 171.581 |
| Flash Point | 160.2±23.7 °C |
| Exact Mass | 171.008713 |
| PSA | 63.32000 |
| LogP | 2.22 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.649 |
| InChIKey | YIYBPEDZAUFQLO-UHFFFAOYSA-N |
| SMILES | Nc1ccc(C(=O)O)cc1Cl |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22 |
| Safety Phrases | S26-S36/37 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2922499990 |
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~92%
4-Amino-3-chlor... CAS#:2486-71-7 |
| Literature: H. LUNDBECK A/S Patent: WO2006/114093 A1, 2006 ; Location in patent: Page/Page column 37 ; WO 2006/114093 A1 |
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~58%
4-Amino-3-chlor... CAS#:2486-71-7 |
| Literature: Vertex Pharmaceuticals Incorporated Patent: US6531474 B1, 2003 ; US 6531474 B1 |
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~%
4-Amino-3-chlor... CAS#:2486-71-7 |
| Literature: WO2005/115147 A2, ; Page/Page column 40 ; |
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4-Amino-3-chlor... CAS#:2486-71-7 |
| Literature: US6028111 A1, ; |
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~61%
4-Amino-3-chlor... CAS#:2486-71-7 |
| Literature: Mukhopadhyay, Sudip; Chandnani, Kavita H.; Chandalia, Sampatraj B. Organic Process Research and Development, 1999 , vol. 3, # 3 p. 196 - 200 |
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4-Amino-3-chlor... CAS#:2486-71-7 |
| Literature: Journal of the American Chemical Society, , vol. 66, p. 1631 |
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4-Amino-3-chlor... CAS#:2486-71-7 |
| Literature: Journal of the American Chemical Society, , vol. 66, p. 1631 |
|
~85%
4-Amino-3-chlor... CAS#:2486-71-7 |
| Literature: Shchel'tsyn, V. K.; Frolova, T. I.; Grudtsyn, Yu. D.; Vandysheva, E. A.; Kaminskii, A. Ya.; Leonova, V. V. Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 11.2 p. 2132 - 2142 Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 11 p. 2401 - 2412 |
| Precursor 7 | |
|---|---|
| DownStream 5 | |
CAS#:95-51-2
CAS#:1019018-13-3
CAS#:113372-69-3| HS Code | 2922499990 |
|---|---|
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Searching for novel scaffold of triazole non-nucleoside inhibitors of HIV-1 reverse transcriptase.
J. Enzyme Inhib. Med. Chem. 31 , 481-9, (2016) Azoles are a promising class of the new generation of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs). From thousands of reported compounds, many possess the same basic structure of an ... |
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Aminobenzoic acid compounds as HOCl traps for activated neutrophils.
Free Radic. Biol. Med. 22(6) , 989-98, (1997) This study was designed to develop traps for hypochlorous acid (HOCl) which could be used to detect HOCl in the microenvironment of activated neutrophils. Reagent HOCl was found to react with para-ami... |
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Name: Binding affinity to human serum albumin at 100 umol/l by equilibrium dialysis techniq...
Source: ChEMBL
Target: Albumin
External Id: CHEMBL3280537
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Name: Lipophilic-hydrophilic balance, Rm of the compound by TLC analysis
Source: ChEMBL
Target: N/A
External Id: CHEMBL3280539
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Name: Dissociation constant, pKa of the compound by spectrophotometric analysis
Source: ChEMBL
Target: N/A
External Id: CHEMBL3280541
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Name: Antimicrobial activity against Escherichia coli assessed as growth inhibition after 2...
Source: ChEMBL
Target: Escherichia coli
External Id: CHEMBL3280540
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| 4-amino-3-chlorbenzoic acid |
| o-chloroaniline-p-carboxylic acid |
| 4-Amino-3-chlorobenzoic acid |
| 4-Amnio-3-chlorobenzioc acid |
| 4-Amino-3-chloro-benzoic acid |
| 4-Amino-3-chlor-benzoesaeure |
| EINECS 219-630-4 |
| 3-chloro-4-aminobenzoic acid |
| MFCD00460423 |