Apoptotic agent-1

Modify Date: 2025-08-26 16:51:47

Apoptotic agent-1 Structure
Apoptotic agent-1 structure
Common Name Apoptotic agent-1
CAS Number 2490538-26-4 Molecular Weight 319.73
Density N/A Boiling Point N/A
Molecular Formula C12H6ClN5O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Apoptotic agent-1


Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].

 Names

Name Apoptotic agent-1

 Apoptotic agent-1 Biological Activity

Description Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].
Related Catalog
In Vitro Apoptotic agent-1 (Compound 8a) shows antiproliferative activity with IC50 values of 53.3, 12.9 and > 100 µM against HepG2, MCF-7 and WI-38 cells, respectively[1].
References

[1]. Haffez H, et al. Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity. Bioorg Chem. 2020 Nov;104:104249.

 Chemical & Physical Properties

Molecular Formula C12H6ClN5O2S
Molecular Weight 319.73
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