LDHA/PDKs-IN-1

Modify Date: 2025-08-25 17:13:00

LDHA/PDKs-IN-1 structure	Common Name	LDHA/PDKs-IN-1
	CAS Number	2490699-40-4	Molecular Weight	360.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₁FN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LDHA/PDKs-IN-1

LDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 0.8 and 0.15 μM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with an EC50 of 13.2 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research of cancer diseases[1].

Name	LDHA/PDKs-IN-1

Description	LDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 0.8 and 0.15 μM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with an EC50 of 13.2 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research of cancer diseases[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> PDK-1 Research Areas >> Cancer
References	[1]. Xiang S, et al. Development of dual inhibitors targeting pyruvate dehydrogenase kinases and human lactate dehydrogenase A: High-throughput virtual screening, synthesis and biological validation. Eur J Med Chem. 2020;203:112579.

Molecular Formula	C₁₉H₂₁FN₂O₄
Molecular Weight	360.38

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

LDHA/PDKs-IN-1

Use of LDHA/PDKs-IN-1

Names

LDHA/PDKs-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.