Urotensin II (human) trifluoroacetate salt structure
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Common Name | Urotensin II (human) trifluoroacetate salt | ||
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CAS Number | 251293-28-4 | Molecular Weight | 1388.57 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C64H85N13O18S2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Urotensin II (human) trifluoroacetate saltUrotensin II (114-124), human, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14. |
Name | Urotensin II (human) |
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Synonym | More Synonyms |
Description | Urotensin II (114-124), human, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14. |
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Related Catalog | |
Target |
GPR14[1] |
In Vitro | Human Urotensin II (U-II) binds to recombinant human GPR14 with high affinity, and the binding is functionally coupled to calcium mobilization. Human Urotensin II induces concentration-dependent increases in intracellular calcium in a HEK-293 cell line expressing human GPR14 (EC50=0:62±0.17 nM, n=6)[1]. |
In Vivo | Human Urotensin II (U-II) markedly increases total peripheral resistance in anaesthetized non-human primates, a response associated with profound cardiac contractile dysfunction[1]. |
References |
Molecular Formula | C64H85N13O18S2 |
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Molecular Weight | 1388.57 |
PSA | 580.00000 |
LogP | 2.88900 |
m.w. 1388.57 c64h85n13o18s2 |
glu-thr-pro-asp-cys-phe-trp-lys-tyr-cys-val hydrochloride |
glu-thr-pro-asp-cys-phe-trp-lys-tyr-cys-val |
urotensin-ii |
h-glu-thr-pro-asp-cys-phe-trp-lys-tyr-cys-val-oh |
GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL(DISULFIDE BRIDGE:CYS5-CYS10) |
Urotensin II (114-124), human |