2,2,6,6-Tetramethylpiperidinooxy
2,2,6,6-Tetramethylpiperidinooxy structure
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Common Name | 2,2,6,6-Tetramethylpiperidinooxy | ||
|---|---|---|---|---|
| CAS Number | 2564-83-2 | Molecular Weight | 156.245 | |
| Density | 1 g/cm3 | Boiling Point | 193°C | |
| Molecular Formula | C10H21NO? | Melting Point | 36-38 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 154 °F | |
| Symbol |
GHS05 |
Signal Word | Danger | |
Use of 2,2,6,6-TetramethylpiperidinooxyTempo is a classic nitroxide radical and is a selective scavenger of mitochondrial ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects[1][2][3][4]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | tempo |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Tempo is a classic nitroxide radical and is a selective scavenger of mitochondrial ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects[1][2][3][4]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1 g/cm3 |
|---|---|
| Boiling Point | 193°C |
| Melting Point | 36-38 °C(lit.) |
| Molecular Formula | C10H21NO? |
| Molecular Weight | 156.245 |
| Flash Point | 154 °F |
| Exact Mass | 156.138840 |
| PSA | 3.24000 |
| LogP | 2.31290 |
| InChIKey | QYTDEUPAUMOIOP-UHFFFAOYSA-N |
| SMILES | CC1(C)CCCC(C)(C)N1[O] |
| Storage condition | 2-8°C |
| Stability | Stable. Incompatible with strong acids, strong oxidizing agents. Refrigerate. |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | C:Corrosive; Xi:Irritant |
| Risk Phrases | R34;R36/37/38 |
| Safety Phrases | S26-S36/37/39-S45-S24/25 |
| RIDADR | UN 3263 8/PG 2 |
| WGK Germany | 3 |
| RTECS | TN8991900 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 29333999 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
|---|---|
| DownStream 8 | |
CAS#:7031-93-8
CAS#:26864-01-7
CAS#:34672-82-7
CAS#:768-66-1
CAS#:45842-10-2
CAS#:113132-33-5
CAS#:56-23-5
CAS#:54051-40-0
CAS#:154554-67-3
CAS#:1311295-90-5
CAS#:4521-28-2
CAS#:502-41-0
CAS#:120881-31-4
CAS#:1889-67-4
CAS#:617-94-7
CAS#:1100308-23-3This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 29333999 |
|---|
This table lists relevant public references with title, journal and publication metadata for this compound.
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Chemical isolation and characterization of different cellulose nanofibers from cotton stalks.
Carbohydr. Polym. 134 , 581-9, (2015) Recently, cellulose nanofibers (CNFs) have received wide attention in green nanomaterial technologies. Production of CNFs from agricultural residues has many economic and environmental advantages. In ... |
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Efficient and simple approaches towards direct oxidative esterification of alcohols.
Chemistry 20(47) , 15618-24, (2014) The present article describes novel oxidative protocols for direct esterification of alcohols. The protocols involve successful demonstrations of both "cross" and "self" esterification of a wide varie... |
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Nanofibrillated Cellulose and Copper Nanoparticles Embedded in Polyvinyl Alcohol Films for Antimicrobial Applications.
Biomed Res. Int. 2015 , 456834, (2015) Our long-term goal is to develop a hybrid cellulose-copper nanoparticle material as a functional nanofiller to be incorporated in thermoplastic resins for efficiently improving their antimicrobial pro... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Antimalarial activity against Plasmodium falciparum NF54 by [3H]hypoxanthine incorpor...
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL1680570
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Name: Cytotoxicity against human A431 cells after 72 hrs by MTT assay
Source: ChEMBL
Target: A-431
External Id: CHEMBL1949353
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Name: Antioxidant activity assessed as ABTS radical scavenging activity after 60 mins
Source: ChEMBL
Target: N/A
External Id: CHEMBL3806886
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Name: Antimalarial activity against Plasmodium falciparum K1 by [3H]hypoxanthine incorporat...
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL1680571
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Name: Cytotoxicity against human A431 cells at 300 uM after 72 hrs by MTT assay
Source: ChEMBL
Target: A-431
External Id: CHEMBL1949354
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Name: Mean surviving fraction of V79 cells following a 12-Gy dose of radiation.
Source: ChEMBL
Target: N/A
External Id: CHEMBL819545
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Name: Mean surviving fraction of V79 cells following a 1-h exposure to H2O2.
Source: ChEMBL
Target: N/A
External Id: CHEMBL819535
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Tanan |
| 2,6,6-Tetramethylpiperidine N-oxide |
| 2,2,6,6-Tetramethyl piperidine-N-oxyl |
| (2,2,6,6-Tetramethyl-1-piperidinyl)oxidanyl |
| 2,2,6,6-tetramethyl-1-piperidinyloxy radical |
| 2,2,6,6-Tetramethylpiperidoxyl |
| free radical,2,2,6,6-Tetramethylpiperidine 1-oxyl |
| 2,2,6,6-Tetramethyl-1-piperidinyloxy |
| 2,2,6,6-Tetramethylpiperidine 1-Oxyl Free Radical |
| 2,2,6,6-Tetramethylpiperidinooxy |
| Tetramethylpiperidinooxy |
| T6NTJ AO B1 B1 F1 F1 &&Free Radical |
| Tanane |
| tetramethylpiperidinenitroxide |
| EINECS 219-888-8 |
| (2,2,6,6-Tetramethylpiperidin-1-yl)oxidanyl |
| TEMPO |
| 2,2,6,6-tetramethylperidinooxy |
| 2,2,6,6-tetramethyl-1-piperidinyloxy,free radical |
| MFCD00009599 |
| 2,2,6,6-Tetramethyl-1-piperidinyloxy,free radical,2,2,6,6-Tetramethylpiperidine 1-oxyl |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular formula of tempo? |
| A: Molecular formula of tempo is C10H21NO?. |
| Q: What is the molecular weight of tempo? |
| A: Molecular weight of tempo is 156.245. |
| Q: What are the uses of tempo? |
| A: Main uses of tempo: Tempo is a classic nitroxide radical and is a selective scavenger of mitochondrial ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects[1][2][3][4]. |
| Q: What is the English name of tempo? |
| A: The English name of tempo is tempo. |
| Q: What is the SMILES notation of tempo? |
| A: SMILES notation of tempo is CC1(C)CCCC(C)(C)N1[O]. |
| Q: What is the InChIKey of tempo? |
| A: InChIKey of tempo is QYTDEUPAUMOIOP-UHFFFAOYSA-N. |
| Q: What is the CAS number of tempo? |
| A: CAS number of tempo is 2564-83-2. |
| Q: What is the polar surface area (PSA) of tempo? |
| A: Polar surface area (PSA) of tempo is 3.24000. |
| Q: What are the upstream materials of tempo? |
| A: Related upstream materials(CAS) of tempo: 7031-93-8;26864-01-7;34672-82-7;768-66-1;45842-10-2;113132-33-5;56-23-5;54051-40-0;154554-67-3. |
| Q: What is the safety information for tempo? |
| A: Safety information for tempo: S26-S36/37/39-S45-S24/25. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |