Velutin

Modify Date: 2025-08-25 15:54:42

Velutin Structure
Velutin structure
 Common Name Velutin
CAS Number 25739-41-7 Molecular Weight 314.289
Density 1.4±0.1 g/cm3 Boiling Point 567.5±50.0 °C at 760 mmHg
Molecular Formula C17H14O6 Melting Point N/A
MSDS N/A Flash Point 213.1±23.6 °C

 Use of Velutin


Velutin is an aglycone extracted from Korean Mistletoe, with inhibitory activity against melanin biosynthesis. Velutin reduces osteoclast differentiation and down-regulates HIF-1α through the NF-κB pathway[1][2].

 Names

Name 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxychromen-4-one
Synonym More Synonyms

 Velutin Biological Activity

Description Velutin is an aglycone extracted from Korean Mistletoe, with inhibitory activity against melanin biosynthesis. Velutin reduces osteoclast differentiation and down-regulates HIF-1α through the NF-κB pathway[1][2].
Related Catalog
References

[1]. Jung SH, et al. Velutin, an Aglycone Extracted from Korean Mistletoe, with Improved Inhibitory Activity against Melanin Biosynthesis. Molecules. 2019 Jul 12;24(14).

[2]. Brito C, et al. Cytotoxicity and potential anti-inflammatory activity of velutin on RAW 264.7 cell line differentiation: Implications in periodontal bone loss. Arch Oral Biol. 2017 Nov;83:348-356

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 567.5±50.0 °C at 760 mmHg
Molecular Formula C17H14O6
Molecular Weight 314.289
Flash Point 213.1±23.6 °C
Exact Mass 314.079041
PSA 89.13000
LogP 2.06
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.646

 Safety Information

Hazard Codes Xi
HS Code 2914509090

 Synthetic Route

5,4'-dihydroxy-7,3'-dimethoxyflavone-4'-O-beta-D-xylopyranosyl-(2a1b)-2a-O-beta-D-xylopyranosyl-(2b1c)-2b-O-beta-D-xylopyranosyl-2c-octadecanoate structure

5,4'-dihydroxy-...

CAS#:1449692-19-6

~%

Velutin Structure

Velutin

CAS#:25739-41-7

Literature: Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048
N/A structure

N/A

CAS#:1449692-20-9

~%

Velutin Structure

Velutin

CAS#:25739-41-7

Literature: Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048
5,4'-dihydroxy-7,3'-dimethoxyflavone-4'-O-beta-D-xylopyranosyl-(2a1b)-2a-O-beta-D-xylopyranosyl-(2b1c)-2b-O-beta-D-xylopyranosyl-2c-octadecanoate structure

5,4'-dihydroxy-...

CAS#:1449692-19-6

~%

D-(+)-Xylose structure

D-(+)-Xylose

CAS#:58-86-6

Velutin Structure

Velutin

CAS#:25739-41-7

stearic acid structure

stearic acid

CAS#:57-11-4

Literature: Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048
N/A structure

N/A

CAS#:1449692-20-9

~%

D-(+)-Xylose structure

D-(+)-Xylose

CAS#:58-86-6

Velutin Structure

Velutin

CAS#:25739-41-7

stearic acid structure

stearic acid

CAS#:57-11-4

Literature: Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048
(-)-5-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-7-methoxy-chroman-4-one structure

(-)-5-hydroxy-2...

CAS#:41877-53-6

~%

Velutin Structure

Velutin

CAS#:25739-41-7

Literature: Geissman Australian Journal of Chemistry, 1958 , vol. 11, p. 376,381
Luteolin structure

Luteolin

CAS#:491-70-3

~%

Diosmetin structure

Diosmetin

CAS#:520-34-3

Chrysoeriol structure

Chrysoeriol

CAS#:491-71-4

Velutin Structure

Velutin

CAS#:25739-41-7

Detail
Literature: Brunet, Gunter; Ibrahim, Ragai K. Phytochemistry (Elsevier), 1980 , vol. 19, p. 741 - 746
4'-Hydroxy-5,7,3'-trimethoxyflavone structure

4'-Hydroxy-5,7,...

CAS#:1239-68-5

~10%

Luteolin 5,3'-dimethyl ether structure

Luteolin 5,3'-d...

CAS#:62346-14-9

Velutin Structure

Velutin

CAS#:25739-41-7

5-Hydroxy-3',4',7-trimethoxyflavone structure

5-Hydroxy-3',4'...

CAS#:29080-58-8

Detail
Literature: Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396
Luteolin 5,3'-dimethyl ether structure

Luteolin 5,3'-d...

CAS#:62346-14-9

~5%

Chrysoeriol structure

Chrysoeriol

CAS#:491-71-4

4'-Methylchrysoeriol structure

4'-Methylchrysoeriol

CAS#:4712-12-3

Velutin Structure

Velutin

CAS#:25739-41-7

Detail
Literature: Geiger, Hans; Casteele, Karel Vande; Sumere, Christiaan F. Van Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1984 , vol. 39, # 3 p. 393 - 396

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

4',5-dihydroxy-3',7-dimethoxyflavone
5,4'-dihydroxy-7,3'-dimethoxyflavone
Flavoyadorigenin B
5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-chromen-4-one
chrysoeriol-7-methyl ether
5,4'-dihydroxy-7,3'-dimethoxylflavone
4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-
luteolin 7,3'-dimethyl ether
Velutin
7,3'-di-O-methylluteolin
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