Thymidine,5'-deoxy-5'-iodo-

Modify Date: 2024-01-09 18:18:39

Thymidine,5'-deoxy-5'-iodo- structure	Common Name	Thymidine,5'-deoxy-5'-iodo-
	CAS Number	25953-14-4	Molecular Weight	352.13
	Density	1.871g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₃IN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thymidine,5'-deoxy-5'-iodo-

5′-Deoxy-5′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5'-iodo-5'-deoxythymidine
Synonym	More Synonyms

Description	5′-Deoxy-5′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.871g/cm3
Molecular Formula	C₁₀H₁₃IN₂O₄
Molecular Weight	352.13
Exact Mass	351.99200
PSA	84.32000
Index of Refraction	1.634

Thymidine

CAS#:50-89-5

~77%

Thymidine,5'-de...

CAS#:25953-14-4

Literature: Vernekar, Sanjeev Kumar V.; Qiu, Li; Zacharias, Jeana; Geraghty, Robert J.; Wang, Zhengqiang MedChemComm, 2014 , vol. 5, # 5 p. 603 - 608

3'-O-Ac-dT

CAS#:21090-30-2

Thymidine,5'-de...

CAS#:25953-14-4

Literature: Michelson; Todd Journal of the Chemical Society, 1955 , p. 816,822

Precursor 2
CAS#:50-89-5 Thymidine CAS#:21090-30-2 3'-O-Ac-dT
DownStream 5
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