5'-DEOXYTHYMIDINE
5'-DEOXYTHYMIDINE structure
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Common Name | 5'-DEOXYTHYMIDINE | ||
|---|---|---|---|---|
| CAS Number | 3458-14-8 | Molecular Weight | 352.13 | |
| Density | 1.344g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C10H13IN2O4 | Melting Point | 192-193ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of 5'-DEOXYTHYMIDINE5′-Deoxythymidine is a thymidine form which 5' position replaced with hydrogen. 5'-deoxy Thymidine is effective against Bacillus subtilis and Staphylococcus aureus. 5′-Deoxythymidine can be used as a research tool for antiviral and anticancer studies[1]. |
| Name | 2′,5′-Dideoxythymidine |
|---|---|
| Synonym | More Synonyms |
| Description | 5′-Deoxythymidine is a thymidine form which 5' position replaced with hydrogen. 5'-deoxy Thymidine is effective against Bacillus subtilis and Staphylococcus aureus. 5′-Deoxythymidine can be used as a research tool for antiviral and anticancer studies[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.344g/cm3 |
|---|---|
| Melting Point | 192-193ºC(lit.) |
| Molecular Formula | C10H13IN2O4 |
| Molecular Weight | 352.13 |
| Exact Mass | 226.09500 |
| PSA | 84.32000 |
| Index of Refraction | 1.559 |
| Storage condition | -20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
~41%
5'-DEOXYTHYMIDINE CAS#:3458-14-8 |
| Literature: Yamazaki, Osamu; Togo, Hideo; Nogami, Genki; Yokoyama, Masataka Bulletin of the Chemical Society of Japan, 1997 , vol. 70, # 10 p. 2519 - 2523 |
|
~88%
5'-DEOXYTHYMIDINE CAS#:3458-14-8 |
| Literature: Wengel; Svendsen; Jorgensen; Nielsen Nucleosides and Nucleotides, 1995 , vol. 14, # 7 p. 1465 - 1479 |
|
~35%
5'-DEOXYTHYMIDINE CAS#:3458-14-8 |
| Literature: Sekine, Mitsuo; Nakanishi, Takeshi Journal of Organic Chemistry, 1990 , vol. 55, # 3 p. 924 - 928 |
|
~%
5'-DEOXYTHYMIDINE CAS#:3458-14-8 |
| Literature: Sekine, Mitsuo; Nakanishi, Takeshi Journal of Organic Chemistry, 1990 , vol. 55, # 3 p. 924 - 928 |
|
~%
5'-DEOXYTHYMIDINE CAS#:3458-14-8 |
| Literature: Michelson; Todd Journal of the Chemical Society, 1955 , p. 816,822 |
|
~%
5'-DEOXYTHYMIDINE CAS#:3458-14-8 |
| Literature: Michelson; Todd Journal of the Chemical Society, 1955 , p. 816,822 |
![1-[(2R,4S,5S)-5-(chloromethyl)-4-hydroxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione structure](https://image.chemsrc.com/caspic/276/25905-50-4.png)
CAS#:61168-97-6
CAS#:65-71-4|
Thymidine inhibits the growth-arrest-specific degradation of thymidine kinase protein in transfected L fibroblasts.
J. Mol. Biol. 265(2) , 153-60, (1997) The expression of murine thymidine kinase (TK) is strictly dependent on the growth state of the cell. Expressing epitope-tagged TK in LTK cells, we have previously shown that low TK enzyme levels in G... |
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Membrane permeation characteristics of 5'-modified thymidine analogs.
Mol. Pharmacol. 41(5) , 950-6, (1992) The membrane permeation characteristics of 5'-deoxythymidine (5'-ddThd) and 5'-azido-5'-deoxythymidine (5'-N3-5'-ddThd) were investigated in human erythrocytes, with an inhibitor-stop assay, at 20 deg... |
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Synthesis and HIV-1 reverse transcriptase inhibitor activity of some 2,5,6-substituted benzoxazole, benzimidazole, benzothiazole and oxazolo(4,5-b)pyridine derivatives.
Arzneimittelforschung 53(4) , 266-71, (2003) In this study, the synthesis of some benzoxazoles and their analogues were described and their antiviral activities were studied together with the previously synthesized 2,5,6-trisubstituted benzoxazo... |
| MFCD00057398 |
| 1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione |
| 5'-Deoxythymidine |