Thymine
Thymine structure
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Common Name | Thymine | ||
|---|---|---|---|---|
| CAS Number | 65-71-4 | Molecular Weight | 126.113 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 403.8±37.0 °C at 760 mmHg | |
| Molecular Formula | C5H6N2O2 | Melting Point | 316 °C | |
| MSDS | Chinese USA | Flash Point | 198.0±26.5 °C | |
Use of ThymineThymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Thymine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 403.8±37.0 °C at 760 mmHg |
| Melting Point | 316 °C |
| Molecular Formula | C5H6N2O2 |
| Molecular Weight | 126.113 |
| Flash Point | 198.0±26.5 °C |
| Exact Mass | 126.042931 |
| PSA | 65.72000 |
| LogP | -2.09 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.614 |
| InChIKey | RWQNBRDOKXIBIV-UHFFFAOYSA-N |
| SMILES | Cc1c[nH]c(=O)[nH]c1=O |
| Storage condition | Store at RT. |
| Stability | Stable. Incompatible with strong oxidizing agents. |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | XP2100000 |
| HS Code | 2933599090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 9 | |
CAS#:22423-26-3
CAS#:636-26-0
CAS#:15981-91-6
CAS#:78450-19-8
CAS#:87781-93-9
CAS#:50-89-5
CAS#:1195-73-9
CAS#:109-72-8
CAS#:4433-40-3
CAS#:1123-21-3
CAS#:2943-56-8
CAS#:13514-92-6
CAS#:2417-22-3
CAS#:696-04-8
CAS#:1124-84-1
CAS#:110815-43-5
CAS#:110815-41-3This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells.
MAbs 7(2) , 403-12, (2015) Linking the heavy chain (HC) and light chain (LC) genes required for monoclonal antibodies (mAb) production on a single cassette using 2A peptides allows control of LC and HC ratio and reduces non-exp... |
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In vitro investigations on the effect of dermal fibroblasts on keratinocyte responses to ultraviolet B radiation.
Photochem. Photobiol. 90(6) , 1332-9, (2014) Exposure to ultraviolet radiation is closely linked to the development of skin cancers in humans. The ultraviolet B (UVB) radiation wavelength (280-320 nm), in particular, causes DNA damage in epiderm... |
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An amplified electrochemical strategy using DNA-QDs dendrimer superstructure for the detection of thymine DNA glycosylase activity.
Biosens. Bioelectron. 71 , 249-55, (2015) A triple-signal amplification strategy was proposed for highly sensitive and selective detection of thymine DNA glycosylase (TDG) by coupling a dendrimer-like DNA label with the electrochemical method... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 5-Methyl-2,4(1H,3H)-pyrimidinedione |
| Clospirazine |
| 5-methylpyrimidine-2,4-dione |
| 5-Methyluracil |
| THYMINE extrapure |
| Thymine |
| 4-Hydroxy-5-methylpyrimidin-2(1H)-one |
| 5-Methylpyrimidine-2,4-diol |
| ThyMine 5GR |
| 5-Methylpyrimidin-2,4(1H,3H)-dion |
| 2,4-dihydroxy-5-methylpyrimidine |
| D-THYMIDINE |
| THYMIN |
| EINECS 200-616-1 |
| 5-Methylpyrimidine-2,4(1H,3H)-dione |
| MFCD00006026 |
| Zidovudine Impurity 3 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of Thymine? |
| A: Main uses of Thymine: Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM. |
| Q: What is the polar surface area (PSA) of Thymine? |
| A: Polar surface area (PSA) of Thymine is 65.72000. |
| Q: What are the upstream materials of Thymine? |
| A: Related upstream materials(CAS) of Thymine: 22423-26-3;636-26-0;15981-91-6;78450-19-8;87781-93-9;50-89-5;1195-73-9;109-72-8. |
| Q: What is the InChIKey of Thymine? |
| A: InChIKey of Thymine is RWQNBRDOKXIBIV-UHFFFAOYSA-N. |
| Q: What English synonyms does Thymine have? |
| A: English synonyms of Thymine: 5-Methyl-2,4(1H,3H)-pyrimidinedione, Clospirazine, 5-methylpyrimidine-2,4-dione, 5-Methyluracil, THYMINE extrapure, Thymine, 4-Hydroxy-5-methylpyrimidin-2(1H)-one, 5-Methylpyrimidine-2,4-diol, ThyMine 5GR, 5-Methylpyrimidin-2,4(1H,3H)-dion, 2,4-dihydroxy-5-methylpyrimidine, D-THYMIDINE, THYMIN, EINECS 200-616-1, 5-Methylpyrimidine-2,4(1H,3H)-dione, MFCD00006026, Zidovudine Impurity 3. |
| Q: What is the CAS number of Thymine? |
| A: CAS number of Thymine is 65-71-4. |
| Q: What is the safety information for Thymine? |
| A: Safety information for Thymine: S22-S24/25. |
| Q: What is the English name of Thymine? |
| A: The English name of Thymine is Thymine. |
| Q: What is the melting point of Thymine? |
| A: Melting point of Thymine is 316 °C. |
| Q: What is the SMILES notation of Thymine? |
| A: SMILES notation of Thymine is Cc1c[nH]c(=O)[nH]c1=O. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |