EphA2 agonist 1

Modify Date: 2024-01-10 21:07:10

EphA2 agonist 1 structure	Common Name	EphA2 agonist 1
	CAS Number	2611459-57-3	Molecular Weight	1019.07
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₀H₅₈N₁₂O₁₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EphA2 agonist 1

EphA2 agonist 1 (Compound 7bg) is a potent EphA2 receptor agonist. EphA2 agonist 1 shows great potency and selectivity toward EphA2 overexpressed glioblastoma cells and stimulates EphA2 phosphorylation[1].

Name	EphA2 agonist 1

Description	EphA2 agonist 1 (Compound 7bg) is a potent EphA2 receptor agonist. EphA2 agonist 1 shows great potency and selectivity toward EphA2 overexpressed glioblastoma cells and stimulates EphA2 phosphorylation[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Ephrin Receptor
Target	EphA2[1]
In Vitro	EphA2 agonist 1 (Compound 7bg) inhibits cell proliferation with IC50 values of 1.90 ± 0.55 μM and 7.91 ± 2.28 μM against U251 EphA2 overexpressed and U251 wild type cells, respectively[1].
References	[1]. Orahoske CM, et al. Dimeric small molecule agonists of EphA2 receptor inhibit glioblastoma cell growth. Bioorg Med Chem. 2020 Sep 15;28(18):115656.

Molecular Formula	C₅₀H₅₈N₁₂O₁₂
Molecular Weight	1019.07

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