PROTAC EZH2 Degrader-1

Modify Date: 2024-01-08 11:38:32

PROTAC EZH2 Degrader-1 Structure
PROTAC EZH2 Degrader-1 structure
 Common Name PROTAC EZH2 Degrader-1
CAS Number 2641601-67-2 Molecular Weight 942.15
Density N/A Boiling Point N/A
Molecular Formula C54H67N7O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC EZH2 Degrader-1


PROTAC EZH2 Degrader-1 (Compound 150d), a potent PROTAC EZH2 Degrader, exerts inhibitory effect on EZH2 methyltransferase activity with the IC50 of 2.7 nM. EZH2 plays an important role in many tumorigenesis and development processes[1].

 Names

Name PROTAC EZH2 Degrader-1

 PROTAC EZH2 Degrader-1 Biological Activity

Description PROTAC EZH2 Degrader-1 (Compound 150d), a potent PROTAC EZH2 Degrader, exerts inhibitory effect on EZH2 methyltransferase activity with the IC50 of 2.7 nM. EZH2 plays an important role in many tumorigenesis and development processes[1].
Related Catalog
Target

EZH2:2.7 nM (IC50)

References

[1]. Juan Xia, et al. Targeting Enhancer of Zeste Homolog 2 for the Treatment of Hematological Malignancies and Solid Tumors: Candidate Structure-Activity Relationships Insights and Evolution Prospects. J Med Chem. 2022 May 26;65(10):7016-7043.

 Chemical & Physical Properties

Molecular Formula C54H67N7O8
Molecular Weight 942.15
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Chemsrc provides PROTAC EZH2 Degrader-1(CAS#:2641601-67-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PROTAC EZH2 Degrader-1 are included as well.>> amp version: PROTAC EZH2 Degrader-1

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