MrgprX2 antagonist-3

Modify Date: 2024-01-09 12:34:56

MrgprX2 antagonist-3 Structure
MrgprX2 antagonist-3 structure
Common Name MrgprX2 antagonist-3
CAS Number 2642174-19-2 Molecular Weight 337.41
Density N/A Boiling Point N/A
Molecular Formula C16H20FN3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MrgprX2 antagonist-3


MrgprX2 antagonist-3 is an MrgprX2 antagonist extracted from patent WO2021092240A1, example E117. MrgprX2 antagonist-3 can be used for the research of inflammatory disorders of the skin[1].

 Names

Name MrgprX2 antagonist-3

 MrgprX2 antagonist-3 Biological Activity

Description MrgprX2 antagonist-3 is an MrgprX2 antagonist extracted from patent WO2021092240A1, example E117. MrgprX2 antagonist-3 can be used for the research of inflammatory disorders of the skin[1].
Related Catalog
Target

MrgprX2[1]

In Vitro MRGPRX2, a member of the Mas-related gene family, was found to be expressed in sensory neurons, mast cells and, most recently, in keratinocytes. MRGPRX2 mRNA is present in adipose tissue, esophagus, urinary bladder, lungs with the highest levels found in skin. Activation of MRGPRX2 leads to mast cell degranulation with subsequent pseudo-allergic reactions[2].
References

[1]. CEVIKBAS F, et, al. Mrgprx2 antagonists for the treatment of inflammatory disorders. WO2021092240A1.

[2]. Porebski G, et, al. Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions. Front Immunol. 2018 Dec 20;9:3027.

 Chemical & Physical Properties

Molecular Formula C16H20FN3O2S
Molecular Weight 337.41
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