BLU-945

Modify Date: 2024-01-02 18:41:44

BLU-945 Structure
BLU-945 structure
Common Name BLU-945
CAS Number 2660250-10-0 Molecular Weight 556.70
Density N/A Boiling Point N/A
Molecular Formula C28H37FN6O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BLU-945


receptor (EGFR). EGFR is a member of the erbB receptor family, which includes transmembrane protein tyrosine kinase receptors. BLU-945 effectively inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation. BLU-945 facilitates efficacious dosing and reduces EGFR-mediated on-target toxicities. S BLU-945 has the potential for the research of cancer disease (extracted from patent WO2021133809A1, compound 112)[1].

 Names

Name BLU-945

 BLU-945 Biological Activity

Description receptor (EGFR). EGFR is a member of the erbB receptor family, which includes transmembrane protein tyrosine kinase receptors. BLU-945 effectively inhibits EGFR with L858R and/or exon 19 deletion mutation, T790M mutation, and C797S mutation. BLU-945 facilitates efficacious dosing and reduces EGFR-mediated on-target toxicities. S BLU-945 has the potential for the research of cancer disease (extracted from patent WO2021133809A1, compound 112)[1].
Related Catalog
References

[1]. John Emmerson Campbell, et al. Inhibitors of mutant forms of egfr. Patent WO2021133809A1.

 Chemical & Physical Properties

Molecular Formula C28H37FN6O3S
Molecular Weight 556.70