2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone

Modify Date: 2025-08-23 12:52:44

2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone Structure
2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone structure
Common Name 2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone
CAS Number 26771-69-7 Molecular Weight 218.173
Density 1.2±0.1 g/cm3 Boiling Point 259.3±40.0 °C at 760 mmHg
Molecular Formula C10H9F3O2 Melting Point 50-52ºC
MSDS N/A Flash Point 107.4±22.2 °C

 Names

Name 2-methoxy-1-[4-(trifluoromethyl)phenyl]ethanone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 259.3±40.0 °C at 760 mmHg
Melting Point 50-52ºC
Molecular Formula C10H9F3O2
Molecular Weight 218.173
Flash Point 107.4±22.2 °C
Exact Mass 218.055466
PSA 26.30000
LogP 2.37
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.450
InChIKey WDXVCXWXZAMAKA-UHFFFAOYSA-N
SMILES COCC(=O)c1ccc(C(F)(F)F)cc1

 Safety Information

Risk Phrases R21/22
Safety Phrases 24/25
HS Code 2914700090

 Synthetic Route

~%

2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone Structure

2-Methoxy-1-[4-...

CAS#:26771-69-7

Literature: CENTRAL GLASS COMPANY, LIMITED Patent: WO2004/14887 A1, 2004 ; Location in patent: Page 30-33 ;

~74%

2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone Structure

2-Methoxy-1-[4-...

CAS#:26771-69-7

Literature: Tagat, Jayaram R.; McCombie, Stuart W.; Nazareno, Dennis; Labroli, Marc A.; Xiao, Yushi; Steensma, Ruo W.; Strizki, Julie M.; Baroudy, Bahige M.; Cox, Kathleen; Lachowicz, Jean; Varty, Geoffrey; Watkins, Robert Journal of Medicinal Chemistry, 2004 , vol. 47, # 10 p. 2405 - 2408

~%

2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone Structure

2-Methoxy-1-[4-...

CAS#:26771-69-7

Literature: Schering Corporation Patent: US2003/208074 A1, 2003 ; Location in patent: Page/Page column 8; 16 ;

~71%

2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone Structure

2-Methoxy-1-[4-...

CAS#:26771-69-7

Literature: Camuzat-Dedenis; Provot; Moskowitz; Mayrargue Synthesis, 1999 , # 9 p. 1558 - 1560

~94%

2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone Structure

2-Methoxy-1-[4-...

CAS#:26771-69-7

Literature: CENTRAL GLASS COMPANY, LIMITED Patent: WO2004/14887 A1, 2004 ; Location in patent: Page 27-28 ;

~94%

2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone Structure

2-Methoxy-1-[4-...

CAS#:26771-69-7

Literature: CENTRAL GLASS COMPANY, LIMITED Patent: WO2004/14887 A1, 2004 ; Location in patent: Page 28 ;

~61%

2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone Structure

2-Methoxy-1-[4-...

CAS#:26771-69-7

Literature: Feng, Dong-Zhi; Song, Yan-Li; Jiang, Xiao-Hua; Chen, Li; Long, Ya-Qiu Organic and Biomolecular Chemistry, 2007 , vol. 5, # 16 p. 2690 - 2697

 Customs

HS Code 2914700090
Summary HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

 Synonyms

2-methoxy-4'-trifluoromethylacetiphenone
4-trifluoromethyl methoxyacetophenone
Ethanone, 2-methoxy-1-[4-(trifluoromethyl)phenyl]-
AC-578
2-methoxy-4'-trifluoromethylacetophenone
2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone
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