ADAMTS-5-IN-3

Modify Date: 2024-01-02 18:04:55

ADAMTS-5-IN-3 Structure
ADAMTS-5-IN-3 structure
Common Name ADAMTS-5-IN-3
CAS Number 2688733-96-0 Molecular Weight 424.32
Density N/A Boiling Point N/A
Molecular Formula C20H23Cl2N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ADAMTS-5-IN-3


ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1].

 Names

Name ADAMTS-5-IN-3

 ADAMTS-5-IN-3 Biological Activity

Description ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1].
Related Catalog
References

[1]. Dong Liu, et al. Adamts inhibitors, preparation methods and medicinal uses thereof. WO2021158626A1.

 Chemical & Physical Properties

Molecular Formula C20H23Cl2N3O3
Molecular Weight 424.32