EGFR-IN-36

Modify Date: 2024-01-14 18:09:14

EGFR-IN-36 structure	Common Name	EGFR-IN-36
	CAS Number	2711105-54-1	Molecular Weight	488.97
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₅ClN₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR-IN-36

EGFR-IN-36 is a potent EGFR inhibitor with IC50s of 19.09 nM, 120.01 nM, 2.35 nM for EGFR (WT), HER2 (WT), HER2 (A775_G776insYVMA), respectively. EGFR-IN-36 has potential for wild and/or mutant EGFR and/or HER2 kinase mediated tumors research[1].

Name	EGFR-IN-36

Description	EGFR-IN-36 is a potent EGFR inhibitor with IC50s of 19.09 nM, 120.01 nM, 2.35 nM for EGFR (WT), HER2 (WT), HER2 (A775_G776insYVMA), respectively. EGFR-IN-36 has potential for wild and/or mutant EGFR and/or HER2 kinase mediated tumors research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR (WT):19.09 nM (IC50) HER2(WT):120.01 nM (IC50) HER2 (A775_G776insYVMA):2.35 nM (IC50)
In Vitro	EGFR-IN-36 (compound 8) inhibits A431 cell (IC50=223.6 nM),A549 cell (IC50=7644.42 nM), H1975 cell (IC50=20.68 nM)[1].
References	[1]. Yihan Wang, et al. Substituted acrylamide derivatives and their compositions and uses. WO2021185348A1.

Molecular Formula	C₂₆H₂₅ClN₆O₂
Molecular Weight	488.97

DC Chemicals Limited
China
Product Name: EGFR-IN-36
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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