Nrf2 activator-6

Modify Date: 2024-01-02 16:33:50

Nrf2 activator-6 structure	Common Name	Nrf2 activator-6
	CAS Number	2728780-74-1	Molecular Weight	614.11
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₃₇ClFN₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Nrf2 activator-6

Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4)[1].

Name	Nrf2 activator-6

Description	Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4)[1].
Related Catalog	Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Cardiovascular Disease
In Vitro	Nrf2 activator-6 (Example 4) 增加 NRF2 介导的基因 NADPH：醌受体氧化还原酶 1 (NQO1) 的 mRNA 水平，EC50 为 0.3 nM[1]。
References	[1]. Cathy Louise LUCAS, et al. Tetrahydroisoquinoline compounds as nrf2 activators. WO2021214470A1.

Molecular Formula	C₃₁H₃₇ClFN₅O₅
Molecular Weight	614.11