1011399-77-1
1011399-77-1 structure
- Name: PPARα activator compound 3
- Chemical Name: 6-Cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
- CAS Number: 1011399-77-1
- Molecular Formula: C19H18FN3O2
- Molecular Weight: 339.363
- Create Date: 2020-01-12 10:02:33
- Modify Date: 2024-07-23 16:55:01
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PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo; reduces plasma triglyceride levels with similar efficiency as fenofibrate in high fructose-fed rats.
| Name | 6-Cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid |
|---|---|
| Synonyms |
6-Cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
MFCD09473550 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-cyclopropyl-1-(4-fluorophenyl)-3-(1-methylethyl)- |
| Description | PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo; reduces plasma triglyceride levels with similar efficiency as fenofibrate in high fructose-fed rats. |
|---|---|
| References | References 1. Tachibana K, et al. J Biol Chem. 2018 May 15. pii: jbc.RA118.002077. View Related Products by Target PPAR |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 452.7±45.0 °C at 760 mmHg |
| Molecular Formula | C19H18FN3O2 |
| Molecular Weight | 339.363 |
| Flash Point | 227.6±28.7 °C |
| Exact Mass | 339.138306 |
| LogP | 4.98 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.684 |