CHK-336

Modify Date: 2025-08-26 20:19:07

CHK-336 Structure
CHK-336 structure
Common Name CHK-336
CAS Number 2743436-86-2 Molecular Weight 530.57
Density N/A Boiling Point N/A
Molecular Formula C24H20F2N4O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CHK-336


CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50<1 nM) that inhibits lactate production in mouse hepatocytes. CHK-336 can be used in the study of hyperoxaluria[1].

 Names

Name CHK-336

 CHK-336 Biological Activity

Description CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50<1 nM) that inhibits lactate production in mouse hepatocytes. CHK-336 can be used in the study of hyperoxaluria[1].
Related Catalog
References

[1]. David Andrew Powell, et al. Substituted pyrazolyl compounds and methods of use thereof. Patent WO2021234547A1.

 Chemical & Physical Properties

Molecular Formula C24H20F2N4O4S2
Molecular Weight 530.57
InChIKey XAHAUTPHLZAEKK-UHFFFAOYSA-N
SMILES NS(=O)(=O)c1ccc(Cc2c(-c3ccc(F)cc3)nn(-c3nc(C(=O)O)cs3)c2CC2CC2)cc1F
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