(R)-Carvedilol-d4

Modify Date: 2024-01-09 10:38:11

(R)-Carvedilol-d4 structure	Common Name	(R)-Carvedilol-d4
	CAS Number	2747915-92-8	Molecular Weight	410.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₂D₄N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (R)-Carvedilol-d4

(R)-Carvedilol-d4 is deuterium labeled (R)-Carvedilol. (R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].

Name	(R)-Carvedilol-d4

Description	(R)-Carvedilol-d4 is deuterium labeled (R)-Carvedilol. (R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Wu T, et al. Protective effects of S-carvedilol on doxorubicin-induced damages to human umbilical vein endothelial cells and rats. J Appl Toxicol. 2019 Aug;39(8):1233-1244.

Molecular Formula	C₂₄H₂₂D₄N₂O₄
Molecular Weight	410.50

(R)-Carvedilol-d4

Use of (R)-Carvedilol-d4

Names

(R)-Carvedilol-d4 Biological Activity

Chemical & Physical Properties