95093-99-5

95093-99-5 structure

Name: (R)-(+)-Carvedilol
Chemical Name: (2R)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
CAS Number: 95093-99-5
Molecular Formula: C₂₄H₂₆N₂O₄
Molecular Weight: 406.47400
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2018-12-07 18:47:18
Modify Date: 2024-01-18 23:34:02
(R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].

Name	(2R)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
Synonyms	(R)-(+)-Carvedilol S-(-)-1-(carbazol-4-yloxy)-3-[[2-(O-methoxyphenoxy)ethyl]amino]-2-propanol (S)-carvedilol (+)-Carvedilol Carvedilol Impurity 10

Description	(R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	β/α-1 adrenergic receptor[1]
References	[1]. Wu T, et al. Protective effects of S-carvedilol on doxorubicin-induced damages to human umbilical vein endothelial cells and rats. J Appl Toxicol. 2019 Aug;39(8):1233-1244.