(R)-(+)-Carvedilol

Modify Date: 2026-08-15 19:39:53

(R)-(+)-Carvedilol Structure
(R)-(+)-Carvedilol structure
Common Name (R)-(+)-Carvedilol
CAS Number 95093-99-5 Molecular Weight 406.47400
Density 1.25g/cm3 Boiling Point 655.2ºC at 760 mmHg
Molecular Formula C24H26N2O4 Melting Point 114-115ºC
MSDS N/A Flash Point 350.1ºC

 Use of (R)-(+)-Carvedilol


(R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].

 Names

Name (2R)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
Synonym More Synonyms

 (R)-(+)-Carvedilol Biological Activity

Description (R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].
Related Catalog
Target

β/α-1 adrenergic receptor[1]

References

[1]. Wu T, et al. Protective effects of S-carvedilol on doxorubicin-induced damages to human umbilical vein endothelial cells and rats. J Appl Toxicol. 2019 Aug;39(8):1233-1244.

 Chemical & Physical Properties

Density 1.25g/cm3
Boiling Point 655.2ºC at 760 mmHg
Melting Point 114-115ºC
Molecular Formula C24H26N2O4
Molecular Weight 406.47400
Flash Point 350.1ºC
Exact Mass 406.18900
PSA 75.74000
LogP 4.12890
Index of Refraction 1.657
InChIKey OGHNVEJMJSYVRP-QGZVFWFLSA-N
SMILES COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12
Storage condition 2-8°C

 (R)-(+)-CarvedilolBioassay

View more

Name: Displacement of [3H]-CGP-12177 from murine beta1-adrenergic receptor expressed in HEK...
Source: ChEMBL
Target: Beta-1 adrenergic receptor
External Id: CHEMBL4397555
Name: Displacement of [3H]-CGP-12177 from human beta2-adrenergic receptor expressed in CHO ...
Source: ChEMBL
Target: Beta-2 adrenergic receptor
External Id: CHEMBL4397556
Name: Induction Ca2+ levels in CHO cells by FLIPR calcium 4 assay
Source: ChEMBL
Target: CHO
External Id: CHEMBL4429652
Name: Displacement of [3H]CGP12177 from human beta2 receptor expressed in CHO cells
Source: ChEMBL
Target: Beta-2 adrenergic receptor
External Id: CHEMBL3801474
Name: Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T c...
Source: ChEMBL
Target: Beta-1 adrenergic receptor
External Id: CHEMBL4397557
Name: Induction Ca2+ levels in CHO cells at 1 uM by FLIPR calcium 4 assay
Source: ChEMBL
Target: CHO
External Id: CHEMBL4429653
Name: Agonist activity at human OX1 receptor expressed in CHO cell membranes assessed as in...
Source: ChEMBL
Target: Orexin/Hypocretin receptor type 1
External Id: CHEMBL4429654
Name: Agonist activity at beta1-adrenergic receptor (unknown origin) expressed in HEK293T c...
Source: ChEMBL
Target: Beta-1 adrenergic receptor
External Id: CHEMBL4397559
Name: Displacement of [125I]-orexin A from human OX1 receptor expressed in CHO cell membran...
Source: ChEMBL
Target: Orexin/Hypocretin receptor type 1
External Id: CHEMBL4429655
Name: Displacement of [125I]-orexin A from human OX2 receptor expressed in CHO cell membran...
Source: ChEMBL
Target: Orexin receptor type 2
External Id: CHEMBL4429656
Total 29, Current Page 1 of 3
1
2
3

 Synonyms

(R)-(+)-Carvedilol
S-(-)-1-(carbazol-4-yloxy)-3-[[2-(O-methoxyphenoxy)ethyl]amino]-2-propanol
(S)-carvedilol
(+)-Carvedilol
Carvedilol Impurity 10
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.