(R)-(+)-Carvedilol

Modify Date: 2024-01-18 23:34:02

(R)-(+)-Carvedilol Structure
(R)-(+)-Carvedilol structure
Common Name (R)-(+)-Carvedilol
CAS Number 95093-99-5 Molecular Weight 406.47400
Density 1.25g/cm3 Boiling Point 655.2ºC at 760 mmHg
Molecular Formula C24H26N2O4 Melting Point 114-115ºC
MSDS N/A Flash Point 350.1ºC

 Use of (R)-(+)-Carvedilol


(R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].

 Names

Name (2R)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
Synonym More Synonyms

 (R)-(+)-Carvedilol Biological Activity

Description (R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].
Related Catalog
Target

β/α-1 adrenergic receptor[1]

References

[1]. Wu T, et al. Protective effects of S-carvedilol on doxorubicin-induced damages to human umbilical vein endothelial cells and rats. J Appl Toxicol. 2019 Aug;39(8):1233-1244.

 Chemical & Physical Properties

Density 1.25g/cm3
Boiling Point 655.2ºC at 760 mmHg
Melting Point 114-115ºC
Molecular Formula C24H26N2O4
Molecular Weight 406.47400
Flash Point 350.1ºC
Exact Mass 406.18900
PSA 75.74000
LogP 4.12890
Index of Refraction 1.657
Storage condition 2-8°C

 Synonyms

(R)-(+)-Carvedilol
S-(-)-1-(carbazol-4-yloxy)-3-[[2-(O-methoxyphenoxy)ethyl]amino]-2-propanol
(S)-carvedilol
(+)-Carvedilol
Carvedilol Impurity 10
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