Chitin synthase inhibitor 4 structure
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Common Name | Chitin synthase inhibitor 4 | ||
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CAS Number | 2755847-31-3 | Molecular Weight | 346.36 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C20H15FN4O | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Chitin synthase inhibitor 4Chitin synthase inhibitor 4 (compound 4fh) is a chitin synthase (CHS) inhibitor with fungicidal effect. Chitin synthase inhibitor 4 is a potential CHS-based fungicide in agriculture[1]. |
Name | Chitin synthase inhibitor 4 |
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Description | Chitin synthase inhibitor 4 (compound 4fh) is a chitin synthase (CHS) inhibitor with fungicidal effect. Chitin synthase inhibitor 4 is a potential CHS-based fungicide in agriculture[1]. |
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Related Catalog | |
In Vitro | Chitin synthase inhibitor 4 shows good antifungal activities against V. mali and S. sclerotiorum with EC50 values of 0.71 and 2.47 μg/mL, respectively[1]. Chitin synthase inhibitor 4 (50 μg/mL) displays potency inhibition against V. mali and S. sclerotiorum with inhibition rates of 90.3% and 88.7%, respectively[1]. Chitin synthase inhibitor 4 (1 μg/mL) blocks the hyphae growth, results abnormal growth, with inducing cell content decreasing, cell wall degradation, and plasmolysis[1]. Chitin synthase inhibitor 4 (50 μM; 3 h) exhibits inhibition against chitin synthase (CHS) and polyoxin D with inhibition rates of 68.08% and 63.84%, respectively[1]. |
In Vivo | Chitin synthase inhibitor 4 (50 μg/mL) has considerable curative and protective effects against S. sclerotiorum vivo, and no obvious phytotoxicity [1]. Chitin synthase inhibitor 4 has low acute toxicity, with no carcinogenic and mutagenic toxicity risk[1]. Animal Model: Rat with Salmonella typhimurium[1] Dosage: As Acute Oral Toxicity for Chemicals-Acute Toxic Class Method Administration: Oral gavage Result: Showed acute toxicity of 3.58 as toxicity grading standard, and negative carcinogenic toxicity, negative mutagenic toxicity. |
References |
Molecular Formula | C20H15FN4O |
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Molecular Weight | 346.36 |