TD-802

Modify Date: 2025-08-25 12:39:00

TD-802 Structure
TD-802 structure
Common Name TD-802
CAS Number 2760703-21-5 Molecular Weight 957.56
Density N/A Boiling Point N/A
Molecular Formula C52H61ClN10O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TD-802


TD-802 (Compound 33c) is an androgen receptor (AR) PROTAC degrader with good microsomal stability. TD-802 has good antitumor efficacy in vivo and can be used for metastatic castration-resistant prostate cancer research[1].

 Names

Name TD-802

 TD-802 Biological Activity

Description TD-802 (Compound 33c) is an androgen receptor (AR) PROTAC degrader with good microsomal stability. TD-802 has good antitumor efficacy in vivo and can be used for metastatic castration-resistant prostate cancer research[1].
Related Catalog
References

[1]. Takwale AD, et al. Design and characterization of cereblon-mediated androgen receptor proteolysis-targeting chimeras. Eur J Med Chem. 2020 Dec 15;208:112769.

 Chemical & Physical Properties

Molecular Formula C52H61ClN10O6
Molecular Weight 957.56
InChIKey DWMRQCSGBKQGKE-UHFFFAOYSA-N
SMILES CC1(C)C(NC(=O)c2ccc(N3CCN(C4CC5(CCN(C(=O)C6CCN(c7ccc8nnn(C9CCC(=O)NC9=O)c(=O)c8c7)CC6)CC5)C4)CC3)cc2)C(C)(C)C1Oc1ccc(C#N)c(Cl)c1
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