Tetramethylthiourea

Modify Date: 2024-01-02 21:59:17

Tetramethylthiourea Structure
Tetramethylthiourea structure
Common Name Tetramethylthiourea
CAS Number 2782-91-4 Molecular Weight 132.227
Density 1.0±0.1 g/cm3 Boiling Point 245.0±9.0 °C at 760 mmHg
Molecular Formula C5H12N2S Melting Point 75-77 °C(lit.)
MSDS Chinese USA Flash Point 102.0±18.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name Tetramethylthiourea
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 245.0±9.0 °C at 760 mmHg
Melting Point 75-77 °C(lit.)
Molecular Formula C5H12N2S
Molecular Weight 132.227
Flash Point 102.0±18.7 °C
Exact Mass 132.072113
PSA 38.57000
LogP 0.49
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.524
Storage condition 2-8°C
Water Solubility 32 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YU2750000
CHEMICAL NAME :
Urea, 1,1,3,3-tetramethyl-2-thio-
CAS REGISTRY NUMBER :
2782-91-4
BEILSTEIN REFERENCE NO. :
1744916
LAST UPDATED :
199710
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C5-H12-N2-S
MOLECULAR WEIGHT :
132.25
WISWESSER LINE NOTATION :
1N1&YUS&N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
920 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2373 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
250 mg/kg
SEX/DURATION :
female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
DOSE :
500 mg/kg
SEX/DURATION :
female 11-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
250 mg/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
100 ug/L
REFERENCE :
CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 20(2),55,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82211 No. of Facilities: 28 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1954 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS YU2750000
HS Code 29309070

 Synthetic Route

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

1,1,3,3-Tetramethylthiourea
N,n,n',n'-tetramethylthiourea
1,1,3,3-Tetramethyl-2-thiourea
Tetramethylthiourea
N,N,N',N'-tetramethyl-2-thiourea
Tetramethyl-2-thiourea
Thiourea, N,N,N',N'-tetramethyl-
EINECS 220-488-0
tetramethyl thiourea
Thiourea,tetramethyl
NA-101
Urea,thio-,tetramethyl
Basthioryl
TMTU
tetramethyl-thioure
MFCD00008324
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