EGFR/CDK2-IN-1
Modify Date: 2025-11-24 18:43:31
EGFR/CDK2-IN-1 structure
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Common Name | EGFR/CDK2-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 2841405-96-5 | Molecular Weight | 387.65 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H12BrClO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EGFR/CDK2-IN-1EGFR/CDK2-IN-1 (Compound 3b) is an EGFR/CDK2 inhibitor. EGFR/CDK2-IN-1 shows good cytotoxicity against MCF7 and HepG2 cells. EGFR/CDK2-IN-1 can be used in cancer research[1]. |
| Name | EGFR/CDK2-IN-1 |
|---|
| Description | EGFR/CDK2-IN-1 (Compound 3b) is an EGFR/CDK2 inhibitor. EGFR/CDK2-IN-1 shows good cytotoxicity against MCF7 and HepG2 cells. EGFR/CDK2-IN-1 can be used in cancer research[1]. |
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| Related Catalog | |
| Target |
EGFR, CDK-2[1]. |
| In Vitro | EGFR/CDK2-IN-1 (0-20 μM; 48 h) shows excellent activity in both MCF7 and HepG2 with IC50 values of 4.1 and 3.5 μM, respectively[1]. Cell Cytotoxicity Assay[1] Cell Line: MCF7, HepG2 cells Concentration: 0-20 μM Incubation Time: 48 h Result: Exhibited good cytotoxic activity in breast and liver cancer cells. |
| Molecular Formula | C19H12BrClO2 |
|---|---|
| Molecular Weight | 387.65 |
| InChIKey | YIOGDNXXYFSGJY-PKNBQFBNSA-N |
| SMILES | O=C(C=Cc1ccc(-c2ccccc2Cl)o1)c1ccc(Br)cc1 |