QL-1200186

Modify Date: 2025-08-26 23:11:28

QL-1200186 Structure
QL-1200186 structure
Common Name QL-1200186
CAS Number 2848664-42-4 Molecular Weight 485.54
Density N/A Boiling Point N/A
Molecular Formula C26H27N7O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of QL-1200186


QL-1200186 is anorally activeand selective inhibitor ofTYK2. Oral administration of QL-1200186, dose-dependently inhibitsinterferon-γ(IFNγ) production afterinterleukin-12(IL-12) challenge and significantly ameliorates skin lesions in psoriatic mice[1].

 Names

Name QL-1200186

 QL-1200186 Biological Activity

Description QL-1200186 is anorally activeand selective inhibitor ofTYK2. Oral administration of QL-1200186, dose-dependently inhibitsinterferon-γ(IFNγ) production afterinterleukin-12(IL-12) challenge and significantly ameliorates skin lesions in psoriatic mice[1].
Related Catalog
References

[1]. Chen CX, et al. A novel highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) can block inflammation- and autoimmune-related pathways. Cell Commun Signal. 2023;21(1):287. Published 2023 Oct 16.  

 Chemical & Physical Properties

Molecular Formula C26H27N7O3
Molecular Weight 485.54
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