CB2R/FAAH modulator-3
Modify Date: 2024-01-12 13:07:41
CB2R/FAAH modulator-3 structure
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Common Name | CB2R/FAAH modulator-3 | ||
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| CAS Number | 2876918-67-9 | Molecular Weight | 341.49 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H31NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CB2R/FAAH modulator-3CB2R/FAAH modulator-3 (compound 27) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-3 are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection[1]. |
| Name | CB2R/FAAH modulator-3 |
|---|
| Description | CB2R/FAAH modulator-3 (compound 27) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-3 are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection[1]. |
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| Related Catalog | |
| Target |
CB1:67.6 nM (Ki) CB2:20.1 nM (Ki) |
| In Vitro | CB2R/FAAH modulator-3 (compound 27)(10 μM) 在未刺激的单核细胞和巨噬细胞中，可以降低促炎细胞因子 TNFα、IFN-γ、IL-1β 和 IL6 的产生[1]。 |
| References |
| Molecular Formula | C22H31NO2 |
|---|---|
| Molecular Weight | 341.49 |