4-ethylresorcinol

Modify Date: 2025-08-20 13:17:11

4-ethylresorcinol Structure
4-ethylresorcinol structure
Common Name 4-ethylresorcinol
CAS Number 2896-60-8 Molecular Weight 138.164
Density 1.2±0.1 g/cm3 Boiling Point 273.8±10.0 °C at 760 mmHg
Molecular Formula C8H10O2 Melting Point 95-98 °C(lit.)
MSDS Chinese USA Flash Point 134.4±13.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 4-ethylresorcinol


4-Ethylresorcinol, a derivative of resorcinol, can act as substrates of tyrosinase. 4-Ethylresorcinol possess hypopigmentary effects. 4-Ethylresorcinol attenuates mRNA and protein expression of tyrosinase-related protein (TRP)-2, and possessed antioxidative effect by inhibiting lipid peroxidation[1][2].

 Names

Name 4-ethylbenzene-1,3-diol
Synonym More Synonyms

 4-ethylresorcinol Biological Activity

Description 4-Ethylresorcinol, a derivative of resorcinol, can act as substrates of tyrosinase. 4-Ethylresorcinol possess hypopigmentary effects. 4-Ethylresorcinol attenuates mRNA and protein expression of tyrosinase-related protein (TRP)-2, and possessed antioxidative effect by inhibiting lipid peroxidation[1][2].
Related Catalog
References

[1]. Jimenez AG, et, al. Characterization of the action of tyrosinase on resorcinols. Bioorg Med Chem. 2016 Sep 15;24(18):4434-4443.

[2]. Lam RYY, et, al. Mechanistic studies of anti-hyperpigmentary compounds: elucidating their inhibitory and regulatory actions. Int J Mol Sci. 2014 Aug 21;15(8):14649-68.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 273.8±10.0 °C at 760 mmHg
Melting Point 95-98 °C(lit.)
Molecular Formula C8H10O2
Molecular Weight 138.164
Flash Point 134.4±13.6 °C
Exact Mass 138.068085
PSA 40.46000
LogP 1.75
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.579
InChIKey VGMJYYDKPUPTID-UHFFFAOYSA-N
SMILES CCc1ccc(O)cc1O

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2942000000

 Synthetic Route

 Customs

HS Code 2907299090
Summary 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

 Articles1

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A simple approach for ultrasensitive detection of bisphenols by multiplexed surface-enhanced Raman scattering.

Anal. Chim. Acta 888 , 118-25, (2015)

Bisphenol A (BPA) is well known for its use in plastic manufacture and thermal paper production despite its risk of health toxicity as an endocrine disruptor in humans. Since the publication of new le...

 4-ethylresorcinolBioassay

View more

Name: Inhibition of mushroom tyrosinase activity using TBC as substrate assessed as recover...
Source: ChEMBL
Target: Polyphenol oxidase 2
External Id: CHEMBL3830501
Name: Substrate activity at mushroom tyrosinase assessed as Kcat for monophenolase activity...
Source: ChEMBL
Target: Polyphenol oxidase 2
External Id: CHEMBL3830503
Name: Substrate activity at mushroom tyrosinase assessed as Kcat/Km ratio for monophenolase...
Source: ChEMBL
Target: Polyphenol oxidase 2
External Id: CHEMBL3830504
Name: Substrate activity at mushroom tyrosinase using TBC as substrate assessed as increase...
Source: ChEMBL
Target: Polyphenol oxidase 2
External Id: CHEMBL3830498
Name: Activity of mushroom tyrosinase using TBC as substrate assessed as accumulation of p-...
Source: ChEMBL
Target: Polyphenol oxidase 2
External Id: CHEMBL3830499
Name: Inactivation of mushroom tyrosinase using TBC as substrate assessed as reduction in p...
Source: ChEMBL
Target: Polyphenol oxidase 2
External Id: CHEMBL3830500
Name: Inactivation of tyrosinase (unknown origin) assessed as initial rate of oxygen utiliz...
Source: ChEMBL
Target: Tyrosinase
External Id: CHEMBL2344050
Name: Inactivation of tyrosinase (unknown origin) assessed as total oxygen uptake using 4-m...
Source: ChEMBL
Target: Tyrosinase
External Id: CHEMBL2344048
Name: Inactivation of mushroom tyrosinase using TBC as substrate assessed as reduction in p...
Source: ChEMBL
Target: Polyphenol oxidase 2
External Id: CHEMBL3830505
Name: Inactivation of tyrosinase (unknown origin) assessed as initial rate of oxygen utiliz...
Source: ChEMBL
Target: Tyrosinase
External Id: CHEMBL2344052
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 Synonyms

1,3-Benzenediol,4-ethyl
1,3-Dihydroxy-4-ethylbenzene
4-ethylresorcinol
EINECS 220-777-1
2,4-Dihydroxyethylbenzene
4-Ethylbenzol-1,3-diol
MFCD00002283
6-Ethylresorcinol
2,4-Dihydroxy-1-ethylbenzene
4-Ethyl-1,3-benzenediol
4-Ethyl-resorcinol
4-ethylbenzene-1,3-diol
Resorcinol,4-ethyl
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