Prednisolone hemisuccinate

Modify Date: 2025-08-25 15:49:35

Prednisolone hemisuccinate Structure
Prednisolone hemisuccinate structure
Common Name Prednisolone hemisuccinate
CAS Number 2920-86-7 Molecular Weight 460.51700
Density 0,86 g/cm3 Boiling Point 358 °C400 mm Hg(lit.)
Molecular Formula C25H32O8 Melting Point 28-32 °C(lit.)
MSDS N/A Flash Point 265°C/15mm

 Use of Prednisolone hemisuccinate


Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.

 Names

Name Prednisolone succinate
Synonym More Synonyms

 Prednisolone hemisuccinate Biological Activity

Description Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions.
Related Catalog

 Chemical & Physical Properties

Density 0,86 g/cm3
Boiling Point 358 °C400 mm Hg(lit.)
Melting Point 28-32 °C(lit.)
Molecular Formula C25H32O8
Molecular Weight 460.51700
Flash Point 265°C/15mm
Exact Mass 460.21000
PSA 138.20000
LogP 1.97330
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.6
Storage condition 2-8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU4153400
CHEMICAL NAME :
Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-, 21-(hydrogen succinate)
CAS REGISTRY NUMBER :
2920-86-7
LAST UPDATED :
199504
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C25-H32-O8
MOLECULAR WEIGHT :
460.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
50 mg/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,216,1986
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
75 mg/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - homeostasis
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,216,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9553 No. of Facilities: 403 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4029 (estimated) No. of Female Employees: 2015 (estimated)

 Safety Information

Risk Phrases 61-40
Safety Phrases S53-S22-S36/37/39-S45
RIDADR NONH for all modes of transport
RTECS TU4153400

 Synthetic Route

~90%

Prednisolone hemisuccinate Structure

Prednisolone he...

CAS#:2920-86-7

Literature: Wang, Chao; Zhao, Ming; Qiu, Xuecai; Peng, Shiqi Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 16 p. 4403 - 4421

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Prednisolone hemisuccinate Structure

Prednisolone he...

CAS#:2920-86-7

Literature: Ferrer, Sandra; Naughton, Declan P.; Threadgill, Michael D. Tetrahedron, 2003 , vol. 59, # 19 p. 3437 - 3444

 Synonyms

MFCD00056465
PREDNISOLONE HEMISUCCINATE
PREDNISOLONE 21-HEMISUCCINATE
prednisolone21-succinate
prednisolonbisuccinat
EINECS 220-861-8
prednisolut
prednisolon hemisuccinate
Prednisolone hemisuccinate (usp)
prednisolonebisuccinate
Prednisolone (hemisuccinate)
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